{"id":"hexcarbacholine","rwe":[],"tags":[{"label":"hexcarbacholine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"calbogen","offLabel":[],"synonyms":["hexacarbacholine bromide","calbogen","carbolonium bromide","hexcarbacholine bromide","imbretil","hexcarbacholine"],"timeline":[],"approvals":[],"brandName":"Calbogen","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"hexcarbacholine","explanation":"Think of the parasympathetic nervous system like the 'brake' in your body's 'car'. When it's stimulated, it helps to slow down your heart rate, calm your digestive system, and promote relaxation. This can be helpful in certain medical conditions, but more research is needed to understand its full effects.","oneSentence":"Calbogen works by stimulating the parasympathetic nervous system, which helps to regulate various bodily functions such as heart rate and digestion.","technicalDetail":"Calbogen is a hexcarbacholine, a type of cholinergic agonist that binds to and activates muscarinic acetylcholine receptors, leading to increased parasympathetic tone and downstream effects on various physiological processes."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3458","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=HEXCARBACHOLINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:53:00.598909","biosimilars":[],"competitors":[],"genericName":"hexcarbacholine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"VG8ANM76JY","CHEBI":"CHEBI:135582","INN_ID":"908","UMLSCUI":"C2828259","ChEMBL_ID":"CHEMBL2110842","PUBCHEM_CID":"71496","SECONDARY_CAS_RN":"13309-41-6","MESH_SUPPLEMENTAL_RECORD_UI":"C007930"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Cardiovascular"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Calbogen, also known as hexcarbacholine, is a small molecule drug in the hexcarbacholine class. Its exact target and mechanism of action are unknown, but it is believed to work by stimulating the parasympathetic nervous system. Calbogen's commercial status and approved indications are unclear, and it is not known whether it is patented or available as a generic. Further research is needed to fully understand its safety profile and potential therapeutic applications. As a result, it is not currently available for use in clinical settings.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}