{"id":"helioblock-sx","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The product is designed to protect skin from harmful UV exposure, likely combining multiple UV filters to achieve broad-spectrum protection (UVA and UVB). As a cosmetic/dermatological product from L'Oréal, it functions as a photoprotective barrier rather than a systemically-acting pharmaceutical agent.","oneSentence":"Helioblock SX is a topical sunscreen agent that provides broad-spectrum UV protection by absorbing and reflecting ultraviolet radiation.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:15:02.110Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"UV protection and photoprotection"}]},"trialDetails":[{"nctId":"NCT00326274","phase":"PHASE3","title":"Clinical Safety Trial of Long-Term Intermittent Use of Helioblock® SX Cream","status":"COMPLETED","sponsor":"Loreal USA","startDate":"2006-05","conditions":"Sunburn","enrollment":""},{"nctId":"NCT00368563","phase":"PHASE2, PHASE3","title":"A Capacitance and Transepidermal Water Loss Test to Determine the Ability of Sunscreen to Moisturize Skin","status":"COMPLETED","sponsor":"Loreal USA","startDate":"2006-08","conditions":"Dry Skin","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1994,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Helioblock SX","genericName":"Helioblock SX","companyName":"Loreal USA","companyId":"loreal-usa","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Helioblock SX is a small molecule intervention used in clinical trials to study its effects on dry skin and sunburn. It was tested in a completed study (NCT00368563) to determine its ability to moisturize skin.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}