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It was originally developed by Schering and is currently owned by the same company. Paxipam is FDA-approved for the treatment of anxiety and is off-patent, meaning it is no longer protected by active patents. As a result, there are currently no generic manufacturers of the drug. Paxipam's commercial status and availability may be subject to change.","approvals":[{"date":"1981-09-24","orphan":false,"company":"SCHERING","regulator":"FDA"}],"brandName":"Paxipam","ecosystem":[{"indication":"Anxiety","otherDrugs":[{"name":"alprazolam","slug":"alprazolam","company":"Pharmacia And Upjohn"},{"name":"chlordiazepoxide","slug":"chlordiazepoxide","company":"Valeant Pharm Intl"},{"name":"chlormezanone","slug":"chlormezanone","company":""},{"name":"clorazepate","slug":"clorazepate","company":"Recordati Rare"}],"globalPrevalence":301000000}],"mechanism":{"target":"GABA-A receptor; anion channel","novelty":"Follow-on","targets":[{"gene":"GABRA1","source":"DrugCentral","target":"GABA-A receptor; anion channel","protein":"Gamma-aminobutyric acid receptor subunit alpha-1"},{"gene":"GABRA2","source":"DrugCentral","target":"GABA-A receptor; anion channel","protein":"Gamma-aminobutyric acid receptor subunit alpha-2"},{"gene":"GABRA3","source":"DrugCentral","target":"GABA-A 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