{"id":"haemostatic-solution-haemoblock-application","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL2108251","moleculeType":"Oligosaccharide"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Haemoblock functions as a local hemostatic solution applied directly to bleeding surfaces to arrest hemorrhage. It likely works through a combination of mechanisms including physical tamponade, activation of the coagulation cascade, and promotion of platelet aggregation at the wound site. The exact composition and mechanism are proprietary to Ryazan State Medical University.","oneSentence":"Haemoblock is a topical haemostatic agent that promotes blood clotting and wound hemostasis through physical and biochemical mechanisms.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T02:40:30.562Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Surgical hemostasis and control of bleeding during surgical procedures"},{"name":"Wound hemostasis in general and specialized surgery"}]},"trialDetails":[{"nctId":"NCT04559646","phase":"","title":"Application of the \"Haemoblock\" in Pacemaker Patients","status":"COMPLETED","sponsor":"Ryazan State Medical University","startDate":"2021-01-01","conditions":"Hematoma Postoperative","enrollment":200}],"_emaApprovals":[],"_faersSignals":[{"count":25533,"reaction":"APPLICATION SITE ERYTHEMA"},{"count":21948,"reaction":"APPLICATION SITE PRURITUS"},{"count":21252,"reaction":"APPLICATION SITE PAIN"},{"count":13381,"reaction":"APPLICATION SITE RASH"},{"count":11974,"reaction":"APPLICATION SITE IRRITATION"},{"count":6936,"reaction":"APPLICATION SITE REACTION"},{"count":6366,"reaction":"APPLICATION SITE VESICLES"},{"count":6063,"reaction":"DRUG INEFFECTIVE"},{"count":4943,"reaction":"OFF LABEL USE"},{"count":4848,"reaction":"APPLICATION SITE SWELLING"}],"_approvalHistory":[{"date":"20060711","type":"SUPPL","sponsor":"NORVIUM BIOSCIENCE","applicationNumber":"NDA050801"},{"date":"20180417","type":"SUPPL","sponsor":"NORVIUM BIOSCIENCE","applicationNumber":"NDA050801"},{"date":"20150120","type":"SUPPL","sponsor":"NORVIUM BIOSCIENCE","applicationNumber":"NDA050801"},{"date":"20041022","type":"ORIG","sponsor":"NORVIUM BIOSCIENCE","applicationNumber":"NDA050801"},{"date":"20120120","type":"SUPPL","sponsor":"NORVIUM BIOSCIENCE","applicationNumber":"NDA050801"},{"date":"20101221","type":"SUPPL","sponsor":"NORVIUM BIOSCIENCE","applicationNumber":"NDA050801"}],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["\"Haemoblock\" application"],"phase":"marketed","status":"active","brandName":"Haemostatic solution \"Haemoblock\" application","genericName":"Haemostatic solution \"Haemoblock\" application","companyName":"Ryazan State Medical University","companyId":"ryazan-state-medical-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Haemoblock is a topical haemostatic agent that promotes blood clotting and wound hemostasis through physical and biochemical mechanisms. Used for Surgical hemostasis and control of bleeding during surgical procedures, Wound hemostasis in general and specialized surgery.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}