{"id":"hachimycin","rwe":[],"tags":[{"label":"hachimycin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"D01AA03","category":"atc"},{"label":"Active","category":"status"},{"label":"Candidiasis","category":"indication"},{"label":"Infection by Trichomonas","category":"indication"},{"label":"Anti-Infective Agents","category":"pharmacology"},{"label":"Antifungal Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"trichonat","offLabel":[],"synonyms":["hachimycin","trichomycin","cabimicina","trichonat","trikomycin"],"timeline":[],"approvals":[],"brandName":"Trichonat","ecosystem":[{"indication":"Candidiasis","otherDrugs":[{"name":"amphotericin B","slug":"amphotericin-b","company":"Apothecon"},{"name":"posaconazole","slug":"posaconazole","company":"Schering"}],"globalPrevalence":138000000},{"indication":"Infection by Trichomonas","otherDrugs":[{"name":"metronidazole","slug":"metronidazole","company":"Gd Searle Llc"},{"name":"secnidazole","slug":"secnidazole","company":"Symbiomix Therapeutics Llc"},{"name":"tinidazole","slug":"tinidazole","company":"Mission Pharma"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"hachimycin","explanation":"Imagine your body's cells as strong, protective walls. Hachimycin disrupts the way these walls are built, causing them to break down and leading to the death of the cells. This helps to eliminate the infection.","oneSentence":"Hachimycin works by inhibiting bacterial cell wall synthesis, ultimately leading to cell lysis and death.","technicalDetail":"Hachimycin exerts its antibacterial effect by binding to the bacterial cell wall, inhibiting the action of enzymes responsible for peptidoglycan synthesis, and ultimately leading to cell lysis and death."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4783","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=HACHIMYCIN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:50:39.934896","biosimilars":[],"competitors":[{"drugName":"nystatin","drugSlug":"nystatin","fdaApproval":"1964-07-08","genericCount":48,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"natamycin","drugSlug":"natamycin","fdaApproval":"1978-10-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"griseofulvin","drugSlug":"griseofulvin","fdaApproval":"1962-08-22","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"hachimycin","indications":{"approved":[{"name":"Candidiasis","source":"DrugCentral","snomedId":78048006,"regulator":"FDA","globalPrevalence":138000000,"prevalenceMethod":"ai-extracted","prevalenceSource":"Lancet Infect Dis, 2018 (PMID:30078662)"},{"name":"Infection by Trichomonas","source":"DrugCentral","snomedId":56335008,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"nystatin","brandName":"nystatin","genericName":"nystatin","approvalYear":"1964","relationship":"same-class"},{"drugId":"natamycin","brandName":"natamycin","genericName":"natamycin","approvalYear":"1978","relationship":"same-class"},{"drugId":"griseofulvin","brandName":"griseofulvin","genericName":"griseofulvin","approvalYear":"1962","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"7073J025LS","CHEBI":"CHEBI:35022","INN_ID":"2833","UMLSCUI":"C0062076","ChEMBL_ID":"CHEMBL2108203","KEGG_DRUG":"D02143","DRUGBANK_ID":"DB13302","PUBCHEM_CID":"24883860","SNOMEDCT_US":"66733001","MESH_SUPPLEMENTAL_RECORD_UI":"C100192"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Infectious Disease"],"atcClassification":{"source":"DrugCentral","atcCode":"D01AA03","allCodes":["D01AA03","G01AA06","J02AA02"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Trichonat (Hachimycin) is a small molecule antibiotic in the hachimycin class, originally developed by an unknown entity and currently owned by an unknown entity. It is used to treat Candidiasis and Infection by Trichomonas. The commercial status of Trichonat is unknown, and it may be patented or generic. Key safety considerations are not well-documented. Trichonat is used to treat infections caused by certain types of fungi and protozoa.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}