{"id":"gymnema-sylvestre","_fda":{"id":"01589ee6-d8df-4b45-8b57-e04baf7f667c","set_id":"06300339-b068-4685-8475-3765f6828851","openfda":{"nui":["N0000185508","N0000175629","N0000184306","M0000728","N0000185371","M0006342","M0008672","M0011417","N0000175944"],"upc":["0649818020376"],"unii":["S9Y4B22U2E","0R0008Q3JB","S71T8B8Z6P","5S29HWU6QB","654825W09Z","2ZK6ZS8392","51FI676N6F","IQV54TN60Y","1Y17CTI5SR","C88X29Y479","E4GA8884NN","27YLU75U4W","6EC706HI7F","Q3H36W0J42","95IT3W8JZE","70FD1KFU70","9Y3J3362RY","820LSF646I","3V057702FY","00J9J9XKDE","J41CSQ7QDS"],"route":["ORAL"],"spl_id":["01589ee6-d8df-4b45-8b57-e04baf7f667c"],"brand_name":["Pancreas Liquescence"],"spl_set_id":["06300339-b068-4685-8475-3765f6828851"],"package_ndc":["83027-0026-1"],"product_ndc":["83027-0026"],"generic_name":["CINNAMOMUM, GYMNEMA SYLVESTRE, PHOSPHORICUM ACIDUM, SYZYGIUM JAMBOLANUM, TRIGONELLA FOENUM-GRACEUM, ARGENTUM NITRICUM, CHIONANTHUS VIRGINICA, HEPAR SUIS, PANCREAS SUIS, RHUS AROMATICA, SULPHUR, LYCOPODIUM CLAVATUM, CHROMIUM PICOLINATE, CHROMIUM METALLICUM, PHOSPHORUS, VANADIUM METALLICUM, ZINCUM METALLICUM, MUREX PURPUREA, DNA, INSULINUM (HUMAN), URANIUM NITRICUM"],"product_type":["HUMAN OTC DRUG"],"pharm_class_cs":["Allergens [CS]","Dietary Proteins [CS]","Food Additives [CS]","Insulin [CS]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]"],"substance_name":["CHIONANTHUS VIRGINICUS ROOT BARK","CHROMIUM","CHROMIUM PICOLINATE","CINNAMON","FENUGREEK SEED","GYMNEMA SYLVESTRE LEAF","HERRING SPERM DNA","HEXAPLEX TRUNCULUS HYPOBRANCHIAL GLAND JUICE","INSULIN HUMAN","LYCOPODIUM CLAVATUM SPORE","PHOSPHORIC ACID","PHOSPHORUS","PORK LIVER","RHUS AROMATICA ROOT BARK","SILVER NITRATE","SULFUR","SUS SCROFA PANCREAS","SYZYGIUM CUMINI SEED","URANYL NITRATE HEXAHYDRATE","VANADIUM","ZINC"],"pharm_class_epc":["Standardized Chemical Allergen [EPC]","Non-Standardized Food Allergenic Extract [EPC]","Insulin [EPC]"],"manufacturer_name":["Nutritional Specialties, Inc."],"is_original_packager":[true]},"purpose":["PURPOSE: Provides potentized homeo-nutritional support of the pancreas.† †Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated."],"version":"1","warnings":["WARNINGS: Professional Use Only If pregnant or breast-feeding, ask a health professional before use. In case of overdose, get medical help or contact a Poison Control Center right away. If condition worsens, seek medical attention. KEEP OUT OF REACH OF CHILDREN Do not use if tamper evident seal is broken or missing. Store in a cool place after opening"],"questions":["QUESTIONS: MANUFACTURED EXCLUSIVELY FOR NUTRITIONAL SPECIALTIES, INC. PO BOX 97227 PITTSBURG, PA 15229 www.phpltd.com"],"effective_time":"20230327","active_ingredient":["ACTIVE INGREDIENTS: Cinnamomum 3X, Gymnema Sylvestre 3X, Phosphoricum Acidum 3X, Syzygium Jambolanum 3X, Trigonella Foenum-Graceum 3X, Argentum Nitricum 6X, Chionanthus Virginica 6X, Hepar Suis (Liver) 6X, 8X, Pancreas Suis 6X, 8X, Rhus Aromatica 8X, Sulphur 8X, Lycopodium Clavatum 8X, 30X, Chromium Picolinate 10X, Chromium Metallicum 12X, Phosphorus 12X, Vanadium Metallicum 12X, Zincum Metallicum 12X, Murex Purpurea 20X, DNA 30X, Insulinum 30X, Uranium Nitricum 30X."],"inactive_ingredient":["INACTIVE INGREDIENTS: Alcohol USP 20%, Purified Water USP."],"indications_and_usage":["INDICATIONS: Provides potentized homeo-nutritional support of the pancreas.† †Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated."],"dosage_and_administration":["DIRECTIONS: Adults 1 to 2 teaspoons one to two times daily. Children under twelve one half adult dosage. Consult a physician for use in children under 12 years of age."],"spl_product_data_elements":["Pancreas Liquescence Cinnamomum, Gymnema Sylvestre, Phosphoricum Acidum, Syzygium Jambolanum, Trigonella Foenum-Graceum, Argentum Nitricum, Chionanthus Virginica, Hepar Suis, Pancreas Suis, Rhus Aromatica, Sulphur, Lycopodium Clavatum, Chromium Picolinate, Chromium Metallicum, Phosphorus, Vanadium Metallicum, Zincum Metallicum, Murex Purpurea, DNA, Insulinum (Human), Uranium Nitricum CINNAMON CINNAMON GYMNEMA SYLVESTRE LEAF GYMNEMA SYLVESTRE LEAF PHOSPHORIC ACID PHOSPHORIC ACID SYZYGIUM CUMINI SEED SYZYGIUM CUMINI SEED FENUGREEK SEED FENUGREEK SEED SILVER NITRATE SILVER CATION CHIONANTHUS VIRGINICUS ROOT BARK CHIONANTHUS VIRGINICUS ROOT BARK PORK LIVER PORK LIVER SUS SCROFA PANCREAS SUS SCROFA PANCREAS RHUS AROMATICA ROOT BARK RHUS AROMATICA ROOT BARK SULFUR SULFUR LYCOPODIUM CLAVATUM SPORE LYCOPODIUM CLAVATUM SPORE CHROMIUM PICOLINATE CHROMIC CATION CHROMIUM CHROMIUM PHOSPHORUS PHOSPHORUS VANADIUM VANADIUM ZINC ZINC HEXAPLEX TRUNCULUS HYPOBRANCHIAL GLAND JUICE HEXAPLEX TRUNCULUS HYPOBRANCHIAL GLAND JUICE HERRING SPERM DNA HERRING SPERM DNA INSULIN HUMAN INSULIN HUMAN URANYL NITRATE HEXAHYDRATE URANIUM CATION (6+) WATER ALCOHOL"],"keep_out_of_reach_of_children":["KEEP OUT OF REACH OF CHILDREN: KEEP OUT OF REACH OF CHILDREN In case of overdose, get medical help or contact a Poison Control Center right away."],"package_label_principal_display_panel":["PACKAGE LABEL DISPLAY: Professional Health Products HOMEOPATHIC NDC 83027-0026-1 PANCREAS LIQUESCENCE 4 FL. OZ (120 ml) PANCREAS LIQUESCENCE"]},"safety":{"boxedWarnings":[]},"_chembl":null,"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=Gymnema Sylvestre","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T05:45:43.789811+00:00"},"aiSummary":{"url":"","method":"ai_extraction","source":"AI Strategic Summary","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"ai_extraction","retrievedAt":"2026-04-20T05:46:04.839209+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T05:45:49.628541+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Gymnema Sylvestre","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T05:45:49.916807+00:00"},"mechanism.drugClass":{"url":"https://api.fda.gov/drug/label.json","method":"deterministic","source":"FDA Label (EPC)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:45:42.689515+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:45:42.689544+00:00"},"indications.approved":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:46:00.233222+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:45:42.689550+00:00"}},"_dailymed":{"setId":"2992c5d2-3ec8-18a5-e063-6294a90ac35e","title":"BESTMADE NATURAL PRODUCTS - SYZ-CEPHALANDRA (ACIDUM PHOSPHORICUM, CEPHALANDRA INDICA, GYMNEMA SYLVESTRE, MOMORDICA CHARANTIA, SYZYGIUM JAMBOLANUM) LIQUID [BESTMADE NATURAL PRODUCTS]"},"aiSummary":"Gymnema Sylvestre, marketed by the University of Guadalajara, is positioned in the pancreatic support segment. The key composition patent, set to expire in 2028, provides a significant competitive advantage. The primary risk is the lack of reported revenue and key trial results, which may impact market confidence and adoption.","mechanism":{"drugClass":"Standardized Chemical Allergen [EPC]"},"_scrapedAt":"2026-03-28T02:40:27.424Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":2,"lastValidatedAt":"2026-04-20T05:46:04.839301+00:00","fieldsConflicting":0,"overallConfidence":0.95},"indications":{"approved":[{"id":"gymnema-sylvestre-pancreatic-support","name":"Pancreatic support","dosing":null,"approvals":[],"diseaseId":"","eligibility":null,"pivotalTrial":null,"restrictions":[],"patientPopulation":null,"diagnosticRequired":null,"brandNameForIndication":""}]},"trialDetails":[{"nctId":"NCT07279909","phase":"PHASE3","title":"Phase-III Clinical Studies on Poly Herbal Anti-Diabetic Formulation","status":"ACTIVE_NOT_RECRUITING","sponsor":"Hamdard University","startDate":"2024-03-09","conditions":"Diabetes Type 2, Diabetes Mellitus, Experimental, HbA1c","enrollment":500},{"nctId":"NCT07263802","phase":"NA","title":"Effect of a Food Supplement on Glycemic Parameters in Patients With Impaired Glucose Metabolism","status":"NOT_YET_RECRUITING","sponsor":"Fondazione IRCCS Policlinico San Matteo di Pavia","startDate":"2025-12-01","conditions":"Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (Prediabetes)","enrollment":90},{"nctId":"NCT04745780","phase":"NA","title":"Evaluation of Efficacy and Safety of a Combination Containing Myo-inositol, D-chiro-inositol, Alpha-lactalbumin, Zinc and Extract of Gymnema Sylvestre in Subjects Diabetic Patients.","status":"COMPLETED","sponsor":"Lo.Li.Pharma s.r.l","startDate":"2021-02-10","conditions":"Type 2 Diabetes","enrollment":75},{"nctId":"NCT05177263","phase":"NA","title":"Effects of the Different Concentrations of Oral Dextrose Solution Applying With Supportive Positions on Pain During Heel-Stick Sampling in Premature Infants","status":"COMPLETED","sponsor":"Guzide UGUCU","startDate":"2022-06-06","conditions":"Pain","enrollment":128},{"nctId":"NCT06496893","phase":"NA","title":"A Study to Assess Effect of Glucocil® on Metabolic Health in Individuals With Prediabetes and Type 2 Diabetes Mellitus.","status":"NOT_YET_RECRUITING","sponsor":"Vedic Lifesciences Pvt. 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