{"id":"gutron-treatment","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Constipation"},{"rate":"5-10%","effect":"Nausea"},{"rate":"5-10%","effect":"Diarrhea"}]},"_chembl":{"chemblId":"CHEMBL7257","moleculeType":"Small molecule","molecularWeight":"218.30"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This leads to a reduction in cholesterol levels in the blood, which can help to lower the risk of cardiovascular events. The exact mechanism of action is not fully understood, but it is thought to involve the inhibition of the apical sodium-dependent bile acid transporter (ASBT).","oneSentence":"Gutron treatment works by inhibiting the reabsorption of bile acids in the ileum.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T02:40:09.321Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypercholesterolemia"}]},"trialDetails":[{"nctId":"NCT04440085","phase":"PHASE4","title":"RaGuS Trial by Postoperative Patients","status":"UNKNOWN","sponsor":"Bürgerspital Solothurn","startDate":"2020-09-14","conditions":"Vasoplegic Syndrome, Sirs Due to Noninfectious Process Without Organ Dysfunction, Orthostatic Hypotension","enrollment":50},{"nctId":"NCT01546506","phase":"PHASE2","title":"Confirmation of the Antiviral Effects of Midodrine Identified With a Gene Expression Signature-based Screening of Inluenza A Virus Infected Cells","status":"COMPLETED","sponsor":"Hospices Civils de Lyon","startDate":"2012-02","conditions":"Influenza A Virus Infection","enrollment":79}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Gutron® treatment","genericName":"Gutron® treatment","companyName":"Hospices Civils de Lyon","companyId":"hospices-civils-de-lyon","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Gutron treatment works by inhibiting the reabsorption of bile acids in the ileum. Used for Hypercholesterolemia.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}