{"id":"guanoxan","rwe":[],"tags":[{"label":"guanoxan","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C02CC03","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["guanoxan sulfate","guanoxan","guanoxane"],"offLabel":[],"synonyms":["guanoxan sulfate","guanoxan","guanoxane"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"guanoxan","explanation":"Imagine your blood vessels as a narrow road. When they're constricted, it's like a traffic jam, and blood pressure goes up. GUANOXAN helps to widen these roads, allowing blood to flow more easily and reducing pressure on the heart.","oneSentence":"GUANOXAN is thought to work by relaxing blood vessels, which can help lower blood pressure.","technicalDetail":"As a guanoxan, GUANOXAN likely acts as a direct vasodilator, possibly through inhibition of sympathetic nervous system activity or direct action on vascular smooth muscle cells, leading to decreased peripheral resistance and lowered blood pressure."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1346","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=GUANOXAN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T13:50:29.732812","biosimilars":[],"competitors":[{"drugName":"betanidine","drugSlug":"betanidine","fdaApproval":"","relationship":"same-class"},{"drugName":"guanethidine","drugSlug":"guanethidine","fdaApproval":"1960-07-05","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"guanoxan","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"betanidine","brandName":"betanidine","genericName":"betanidine","approvalYear":"","relationship":"same-class"},{"drugId":"guanethidine","brandName":"guanethidine","genericName":"guanethidine","approvalYear":"1960","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"9V0MRL0R5Y","CHEBI":"CHEBI:134871","INN_ID":"1826","UMLSCUI":"C0018320","ChEMBL_ID":"CHEMBL76725","KEGG_DRUG":"D04399","DRUGBANK_ID":"DB13211","PUBCHEM_CID":"16564","SECONDARY_CAS_RN":"5714-04-5","MESH_SUPPLEMENTAL_RECORD_UI":"C073344"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":76,"therapeuticAreas":["Hematology"],"atcClassification":{"source":"DrugCentral","atcCode":"C02CC03","allCodes":["C02CC03"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"GUANOXAN","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"GUANOXAN is a small molecule drug in the guanoxan class, but specific details about its development, approval status, and commercial availability are not readily available. As a guanoxan, it is likely a vasodilator, but its exact mechanism and target are unknown. Further research is needed to understand its potential therapeutic applications and safety profile. Its commercial status, including patent status and generic availability, is also unclear. Overall, GUANOXAN appears to be a relatively obscure compound with limited information available.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}