{"id":"guanoclor","rwe":[{"pmid":"8257728","year":"1993","title":"Spectrophotometric analysis of some guanidino drugs by acid-dye and charge-transfer complexation methods.","finding":"","journal":"Journal of pharmaceutical and biomedical analysis","studyType":"Clinical Study"},{"pmid":"5591","year":"1976","title":"Conformational populations for antihistamines and antihypertensives in solution.","finding":"","journal":"Journal of pharmaceutical sciences","studyType":"Clinical Study"},{"pmid":"4929159","year":"1971","title":"A comparison of guanoclor and methyldopa in the treatment of severe hypertension.","finding":"","journal":"The British journal of clinical practice","studyType":"Clinical Study"},{"pmid":"4870898","year":"1967","title":"Clinical assessment of the new antihypertensive Compound--1029 (Vatensol)--Guanoclor.","finding":"","journal":"Indian heart journal","studyType":"Clinical Study"},{"pmid":"6058648","year":"1967","title":"Current therapeutics CXXXV.--Guanoclor.","finding":"","journal":"The Practitioner","studyType":"Clinical Study"}],"tags":[{"label":"guanoclor","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C02CC05","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"guanochlorine","offLabel":[],"synonyms":["guanoclor","guanochlorine"],"timeline":[],"approvals":[],"brandName":"Guanochlorine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"guanoclor","explanation":"Imagine your body's cells are like locks, and guanochlorine is a key that fits into one of those locks. When it binds to the lock, it can either turn it on or off, depending on the type of lock and the key's shape. However, the specific lock and key in this case are unknown, so we can't say exactly how guanochlorine works.","oneSentence":"Guanochlorine is thought to work by interacting with a specific biological target, but its exact mechanism is not well understood.","technicalDetail":"Guanochlorine's mechanism of action is not well established, but it is believed to involve interaction with a specific biological target, possibly a receptor or enzyme, to produce its therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4564","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=GUANOCLOR","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:58:33.177561","biosimilars":[],"competitors":[{"drugName":"betanidine","drugSlug":"betanidine","fdaApproval":"","relationship":"same-class"},{"drugName":"guanethidine","drugSlug":"guanethidine","fdaApproval":"1960-07-05","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"guanoclor","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"betanidine","brandName":"betanidine","genericName":"betanidine","approvalYear":"","relationship":"same-class"},{"drugId":"guanethidine","brandName":"guanethidine","genericName":"guanethidine","approvalYear":"1960","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"M4HBT852YO","CHEBI":"CHEBI:135992","INN_ID":"1827","UMLSCUI":"C0061964","ChEMBL_ID":"CHEMBL2110641","DRUGBANK_ID":"DB13779","PUBCHEM_CID":"71835","MESH_SUPPLEMENTAL_RECORD_UI":"C012340"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":8,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"C02CC05","allCodes":["C02CC05"]},"biosimilarFilings":[],"recentPublications":[{"date":"1993 Aug","pmid":"8257728","title":"Spectrophotometric analysis of some guanidino drugs by acid-dye and charge-transfer complexation methods.","journal":"Journal of pharmaceutical and biomedical analysis"},{"date":"1976 Apr","pmid":"5591","title":"Conformational populations for antihistamines and antihypertensives in solution.","journal":"Journal of pharmaceutical sciences"},{"date":"1971 Mar","pmid":"4929159","title":"A comparison of guanoclor and methyldopa in the treatment of severe hypertension.","journal":"The British journal of clinical practice"},{"date":"1967 Oct","pmid":"4870898","title":"Clinical assessment of the new antihypertensive Compound--1029 (Vatensol)--Guanoclor.","journal":"Indian heart journal"},{"date":"1967 Aug","pmid":"6058648","title":"Current therapeutics CXXXV.--Guanoclor.","journal":"The Practitioner"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Guanochlorine (GUANOCLOR) is a small molecule drug in the guanoclor class, but its target and mechanism of action are unknown. Its commercial status and approved indications are also unclear. As a result, key safety considerations and pharmacokinetic properties such as half-life and bioavailability are not well established. Further research is needed to fully understand this compound. Its ownership and patent status are also unknown.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}