{"id":"guaiacol-phosphate","rwe":[{"pmid":"41439388","year":"2026","title":"Niobium Phosphate-Modified HY Zeolite with Enhanced Acidity and Hydroxyl Density for Efficient Alkylation of Bio-Oil Phenolics.","finding":"","journal":"Journal of agricultural and food chemistry","studyType":"Clinical Study"},{"pmid":"41184398","year":"2025","title":"Improvement of durum wheat growth under combined abiotic stresses by multitolerant strain of Pantoea agglomerans for sustainable agricultural approach.","finding":"","journal":"Scientific reports","studyType":"Clinical Study"},{"pmid":"41097488","year":"2025","title":"Supplementation with Probiotic Camel Milk Powder Improves Serum Glucose and Cholesterol as Well as the Related Cytokines in Patients with Type 2 Diabetes Mellitus.","finding":"","journal":"Foods (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"40424629","year":"2025","title":"Formation of Colchicine-incorporated Hybrid Nanoflower With an Intrinsic Peroxidase-Mimic and Enhanced Antimicrobial Activities.","finding":"","journal":"Chemistry & biodiversity","studyType":"Clinical Study"},{"pmid":"39754227","year":"2025","title":"Synthesizing hybrid copper phosphate (Cu(3)(PO(4))(2)) nanoflowers using Cu(+2) and shed snakeskin: antioxidant, antibacterial, anticancer, guaiacol, anionic, and cationic dye degradation properties.","finding":"","journal":"Journal of biological engineering","studyType":"Clinical Study"}],"tags":[{"label":"guaiacol phosphate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["guaiacol phosphate"],"offLabel":[],"synonyms":["guaiacol phosphate"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"guaiacol phosphate","explanation":"Imagine your body's cells have locks on them, and guaiacol phosphate is a key that fits into one of those locks. When it binds to the lock, it triggers a series of events that ultimately lead to the desired therapeutic effect. However, the exact lock and key mechanism for guaiacol phosphate is not yet fully understood.","oneSentence":"Guaiacol phosphate is thought to work by interacting with a specific molecular target to produce a therapeutic effect.","technicalDetail":"Guaiacol phosphate is a small molecule that binds to a specific protein or receptor, altering its activity and leading to changes in downstream signaling pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3452","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=guaiacol%20phosphate","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=guaiacol phosphate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T13:49:57.460158","biosimilars":[],"competitors":[],"genericName":"guaiacol phosphate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT02157649","phase":"PHASE1","title":"Single Dose Trial of Extended Release Combination Tablet Codeine and Guaifenesin","status":"COMPLETED","sponsor":"Nexgen Pharma, Inc","startDate":"2014-06","conditions":["Cough"],"enrollment":26,"completionDate":"2014-09"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"12074","NDDF":"003178","UNII":"56492O1F0U","CHEBI":"CHEBI:28591","VANDF":"4020199","RXNORM":"5031","UMLSCUI":"C0018304","DRUGBANK_ID":"DB11359","PDB_CHEM_ID":" JZ3","PUBCHEM_CID":"68420","SNOMEDCT_US":"424656002","MESH_DESCRIPTOR_UI":"D006139"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":106,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 Jan 14","pmid":"41439388","title":"Niobium Phosphate-Modified HY Zeolite with Enhanced Acidity and Hydroxyl Density for Efficient Alkylation of Bio-Oil Phenolics.","journal":"Journal of agricultural and food chemistry"},{"date":"2025 Nov 3","pmid":"41184398","title":"Improvement of durum wheat growth under combined abiotic stresses by multitolerant strain of Pantoea agglomerans for sustainable agricultural approach.","journal":"Scientific reports"},{"date":"2025 Sep 24","pmid":"41097488","title":"Supplementation with Probiotic Camel Milk Powder Improves Serum Glucose and Cholesterol as Well as the Related Cytokines in Patients with Type 2 Diabetes Mellitus.","journal":"Foods (Basel, Switzerland)"},{"date":"2025 Oct","pmid":"40424629","title":"Formation of Colchicine-incorporated Hybrid Nanoflower With an Intrinsic Peroxidase-Mimic and Enhanced Antimicrobial Activities.","journal":"Chemistry & biodiversity"},{"date":"2025 Jan 3","pmid":"39754227","title":"Synthesizing hybrid copper phosphate (Cu(3)(PO(4))(2)) nanoflowers using Cu(+2) and shed snakeskin: antioxidant, antibacterial, anticancer, guaiacol, anionic, and cationic dye degradation properties.","journal":"Journal of biological engineering"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"guaiacol phosphate","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Guaiacol phosphate is a small molecule drug in the guaiacol phosphate class, but its target and approved indications are unknown. Its commercial status, including whether it is patented or generic, and whether it is off-patent, is also not available. As a result, key safety considerations and pharmacokinetic properties such as half-life and bioavailability are also unknown. Further research is needed to understand this compound's mechanism of action and clinical utility. It is not currently approved by the FDA.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}