{"id":"gsk-biologicals-influenza-vaccine-gsk576389a","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain or erythema"},{"rate":null,"effect":"Myalgia"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Fatigue"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"GSK576389A is an investigational influenza vaccine designed to elicit both humoral and cellular immune responses against influenza virus strains. By presenting viral antigens to the immune system, the vaccine trains B cells and T cells to recognize and neutralize the virus upon natural exposure, reducing infection risk and disease severity.","oneSentence":"This vaccine stimulates the immune system to recognize and respond to influenza virus antigens, providing protection against seasonal influenza infection.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:47:37.015Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Seasonal influenza prevention in adults"}]},"trialDetails":[{"nctId":"NCT00532298","phase":"PHASE2","title":"Non-Inferiority of Various GSK Bio's Influenza Vaccine Presentations in Adults Aged 65 Years and Over","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-09-20","conditions":"Influenza","enrollment":1596},{"nctId":"NCT00633074","phase":"PHASE2","title":"Non-inferiority Study of GSK Biologicals' Influenza Vaccine GSK576389A Using Different Formulations","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2008-03-03","conditions":"Influenza","enrollment":720},{"nctId":"NCT00540592","phase":"PHASE2","title":"Immunogenicity and Safety Study to Evaluate Different Formulations of GSK Biologicals' Influenza Vaccine GSK576389A","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-10-08","conditions":"Influenza","enrollment":2007},{"nctId":"NCT00538213","phase":"PHASE2","title":"Evaluation of Safety and Immunogenicity of GSK Bio's Influenza Vaccine GSK576389A After Repeated Vaccination in Elderly Adults","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-10-15","conditions":"Influenza","enrollment":133},{"nctId":"NCT00538473","phase":"PHASE2","title":"Evaluate Safety and Immunogenicity of GSK Bio's Influenza Vaccine GSK576389A After Repeated Vaccination in Elderly Adults","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-10-23","conditions":"Influenza","enrollment":68},{"nctId":"NCT00529516","phase":"PHASE3","title":"Evaluate Safety & Immunogenicity of GSK Bio's Influenza Vaccine GSK576389A After Repeated Vaccination in Elderly Adults","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-10-15","conditions":"Influenza","enrollment":1252}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"GSK Biologicals Influenza Vaccine GSK576389A","genericName":"GSK Biologicals Influenza Vaccine GSK576389A","companyName":"GlaxoSmithKline","companyId":"gsk","modality":"Biologic","firstApprovalDate":"","aiSummary":"This vaccine stimulates the immune system to recognize and respond to influenza virus antigens, providing protection against seasonal influenza infection. Used for Seasonal influenza prevention in adults.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}