{"id":"group-iii-serratiopeptidase-group","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Allergic reactions"},{"rate":null,"effect":"Bleeding (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Serratiopeptidase is a proteolytic enzyme derived from Serratia marcescens bacteria that selectively degrades inflammatory proteins, fibrin, and damaged tissue while sparing healthy tissue. It reduces swelling, improves blood flow, and facilitates the clearance of inflammatory exudate, making it useful in conditions characterized by inflammation and tissue damage.","oneSentence":"Serratiopeptidase is a serine protease enzyme that breaks down non-structural proteins and fibrin, reducing inflammation and promoting tissue repair.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:47:34.994Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Post-operative inflammation and swelling"},{"name":"Musculoskeletal pain and inflammation"},{"name":"Sinusitis and ENT inflammation"},{"name":"Fibrocystic breast disease"}]},"trialDetails":[{"nctId":"NCT07146997","phase":"PHASE3","title":"Evaluating the Combined Effect of Oral Premedications on Inferior Alveolar Nerve Block Effectiveness","status":"COMPLETED","sponsor":"Zahoor khan","startDate":"2023-11-23","conditions":"Symptomatic Irreversible Pulpitis","enrollment":96}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Group III - Serratiopeptidase Group","genericName":"Group III - Serratiopeptidase Group","companyName":"Zahoor khan","companyId":"zahoor-khan","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Serratiopeptidase is a serine protease enzyme that breaks down non-structural proteins and fibrin, reducing inflammation and promoting tissue repair. Used for Post-operative inflammation and swelling, Musculoskeletal pain and inflammation, Sinusitis and ENT inflammation.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}