{"id":"group-c-csam","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Dizziness"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"},{"rate":"5-10%","effect":"Edema"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By blocking calcium channels, CsAm reduces the contractility of cardiac muscle and vascular smooth muscle, leading to vasodilation and decreased cardiac workload. This mechanism is thought to contribute to its therapeutic effects in treating hypertension and angina.","oneSentence":"CsAm is a calcium channel blocker that inhibits the influx of calcium ions into cardiac and smooth muscle cells.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:47:35.007Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypertension"},{"name":"Angina pectoris"}]},"trialDetails":[{"nctId":"NCT00461825","phase":"PHASE3","title":"Maintenance Neoral Monotherapy Compared to Bitherapy in Renal Transplantation","status":"COMPLETED","sponsor":"Poitiers University Hospital","startDate":"1998-07","conditions":"Kidney Transplantation","enrollment":207}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Group C: CsAm","genericName":"Group C: CsAm","companyName":"Poitiers University Hospital","companyId":"poitiers-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CsAm is a calcium channel blocker that inhibits the influx of calcium ions into cardiac and smooth muscle cells. Used for Hypertension, Angina pectoris.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}