{"id":"grass-2800-bau","safety":{"commonSideEffects":[{"rate":"20-40","effect":"Local reactions at injection site (itching, swelling, erythema)"},{"rate":"5-15","effect":"Oral pruritus"},{"rate":"<1","effect":"Systemic allergic reactions"},{"rate":"<0.1","effect":"Anaphylaxis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is an allergen immunotherapy (AIT) product containing standardized grass pollen allergens measured in Biological Activity Units (BAU). It works by gradually inducing immune tolerance to grass pollen antigens, shifting the immune response from IgE-mediated (allergic) to IgG-mediated (protective) antibodies and promoting regulatory T cells. With repeated administration, patients develop reduced sensitivity to natural grass pollen exposure.","oneSentence":"GRASS 2800 BAU is a grass pollen allergen extract that desensitizes the immune system to grass pollen through repeated exposure, reducing allergic responses.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:31:03.641Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Allergic rhinitis and/or allergic asthma caused by grass pollen"}]},"trialDetails":[{"nctId":"NCT04502966","phase":"PHASE2","title":"Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2020-11-09","conditions":"Allergic Rhinoconjunctivitis, Grass Pollen Allergy","enrollment":108},{"nctId":"NCT05119751","phase":"PHASE4","title":"Vestibular Versus Sublingual Route of AIT Tablets","status":"COMPLETED","sponsor":"Clinique Spécialisée en Allergies de la Capitale","startDate":"2021-10-25","conditions":"Hypersensitivity","enrollment":172},{"nctId":"NCT02394600","phase":"PHASE4","title":"The Impact of Grass SLIT Treatment on Birch Pollen Induced Allergic Rhinitis - a Pilot Evaluation","status":"COMPLETED","sponsor":"Queen's University","startDate":"2015-04","conditions":"Allergic Rhinoconjunctivitis","enrollment":93},{"nctId":"NCT02256553","phase":"PHASE4","title":"Safety Study of MK-3641 and MK-7243 Co-administered in Adult Participants With Ragweed and Grass Pollen Induced Allergic Rhinitis (P08607, MK-3641-006)","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2014-10","conditions":"Rhinitis, Allergic, Seasonal","enrollment":102},{"nctId":"NCT00562159","phase":"PHASE3","title":"Efficacy and Safety of Grass Sublingual Tablet in Adults (P05238 AM3)(COMPLETED)","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2007-11","conditions":"Rhinoconjunctivitis, Rhinitis, Conjunctivitis","enrollment":439}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["GRASTEK"],"phase":"marketed","status":"active","brandName":"GRASS 2800 BAU","genericName":"GRASS 2800 BAU","companyName":"Clinique Spécialisée en Allergies de la Capitale","companyId":"clinique-sp-cialis-e-en-allergies-de-la-capitale","modality":"Small molecule","firstApprovalDate":"","aiSummary":"GRASS 2800 BAU is a grass pollen allergen extract that desensitizes the immune system to grass pollen through repeated exposure, reducing allergic responses. Used for Allergic rhinitis and/or allergic asthma caused by grass pollen.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}