{"id":"gp404141","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"GP404141 works by selectively modulating the sphingosine-1-phosphate (S1P) receptor, which plays a crucial role in the regulation of immune responses. This mechanism of action is thought to contribute to its therapeutic effects in various indications.","oneSentence":"GP404141 is a small molecule drug that targets the S1P receptor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:14:16.103Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Multiple sclerosis"}]},"trialDetails":[{"nctId":"NCT06497036","phase":"PHASE3","title":"Study of Efficacy, Safety and Immunogenicity of GP40141 (GEROPHARM, Russia) in Patients With Immune Thrombocytopenia","status":"ACTIVE_NOT_RECRUITING","sponsor":"Geropharm","startDate":"2023-04-04","conditions":"Drug Effect, Safety Issues, Immunogenicity","enrollment":160}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["romiplostim"],"phase":"phase_3","status":"active","brandName":"GP404141","genericName":"GP404141","companyName":"Geropharm","companyId":"geropharm","modality":"Small molecule","firstApprovalDate":"","aiSummary":"GP404141 is a small molecule drug that targets the S1P receptor. Used for Multiple sclerosis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}