{"id":"glypinamide","rwe":[],"tags":[{"label":"glypinamide","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"parinase","offLabel":[],"synonyms":["glypinamide","azepinamide","parinase"],"timeline":[],"approvals":[],"brandName":"Parinase","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"glypinamide","explanation":"Imagine your nerve cells are like electrical wires. Parinase helps control the flow of electrical signals by adjusting the channels that allow these signals to pass through. This can help regulate various bodily functions, but the exact details of how it works are still unclear.","oneSentence":"Parinase works by modulating ion channels in the nervous system.","technicalDetail":"As a glypinamide, Parinase likely acts as a potassium channel opener, increasing the flow of potassium ions out of the cell and hyperpolarizing the membrane, which can lead to a decrease in neuronal excitability."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3449","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=GLYPINAMIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T13:49:34.260225","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:16:36.009472+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[],"genericName":"glypinamide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"ORE084U8IP","CHEBI":"CHEBI:135415","INN_ID":"1511","UMLSCUI":"C1880993","ChEMBL_ID":"CHEMBL2106693","PUBCHEM_CID":"219111"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Parinase (GLYPINAMIDE) is a small molecule drug in the glypinamide class, but its target and exact mechanism of action are unknown. It is not clear if it is FDA-approved or commercially available. There is limited information available on its pharmacokinetic properties, such as half-life and bioavailability. Parinase is not listed as an off-patent or generic medication. Further research is needed to understand its clinical use and safety profile.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:16:36.009472+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}