{"id":"glucose-1-phosphate","rwe":[{"pmid":"41871161","year":"2026","title":"Functional and molecular characterization of Aspergillus fumigatus phosphoglucomutase (Pgm): a potential target for antifungal therapy.","finding":"","journal":"Journal of medical microbiology","studyType":"Clinical Study"},{"pmid":"41866930","year":"2026","title":"Diet, gut microbiota and urinary metabolite profiles associated with lunularin metabotypes in young Chinese adults.","finding":"","journal":"Food & function","studyType":"Clinical Study"},{"pmid":"41860213","year":"2026","title":"Endocrine Disruptor 2,7-Dibromocarbazole Disrupts Energy Metabolism and Alters Locomotor Behavior in Juvenile Zebrafish.","finding":"","journal":"Chemical research in toxicology","studyType":"Clinical Study"},{"pmid":"41846136","year":"2026","title":"Boron fortifies a dual barrier in rice roots: How Casparian strip reinforcement and cell wall remodeling restrict cadmium entry.","finding":"","journal":"Journal of hazardous materials","studyType":"Clinical Study"},{"pmid":"41832017","year":"2026","title":"Programmable amylose architectures via α-glucan phosphorylase coupling: From process variables to structure-property map.","finding":"","journal":"Carbohydrate polymers","studyType":"Clinical Study"}],"tags":[{"label":"glucose-1-phosphate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Flavoring Agents","category":"pharmacology"},{"label":"Food Additives","category":"pharmacology"},{"label":"Sweetening Agents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":["NCT06806345","NCT04264897","NCT00795678","NCT02485158","NCT01444651","NCT02390180","NCT02136329","NCT02528461","NCT02511041"],"aliases":[],"patents":[],"pricing":[],"allNames":"glucose monophosphate","offLabel":[],"synonyms":["glucose-1-phosphate","alpha-glucose-1-phosphate","D-Glucose, 1-(dihydrogen phosphate)","glucose monophosphate","alpha-D-Glucopyranosyl phosphate"],"timeline":[],"approvals":[],"brandName":"Glucose Monophosphate","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"glucose-1-phosphate","explanation":"Glucose-1-phosphate is a molecule that plays a role in how our bodies use glucose, a type of sugar for energy. It helps regulate the flow of glucose into cells, which is important for maintaining healthy blood sugar levels. By influencing this process, glucose-1-phosphate may help treat conditions related to glucose metabolism.","oneSentence":"Glucose-1-phosphate is thought to influence glucose metabolism.","technicalDetail":"Glucose-1-phosphate is a phosphorylated derivative of glucose that is involved in the glycolytic pathway, specifically in the conversion of glucose-6-phosphate to fructose-6-phosphate."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3265","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=glucose-1-phosphate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:46:19.540744","biosimilars":[],"competitors":[],"dataSources":[{"url":"https://clinicaltrials.gov","name":"ClinicalTrials.gov","fields":["trialDetails","trials"],"retrievedDate":"2026-04-07"},{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"glucose-1-phosphate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT06806345","phase":"Phase 1","title":"Effect of Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopausal Women","status":"RECRUITING","sponsor":"Cairo University","isPivotal":false,"enrollment":40,"indication":"Insulin Resistance Syndrome","completionDate":"2025-04-28"},{"nctId":"NCT04264897","phase":"Phase 3","title":"Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging","status":"COMPLETED","sponsor":"Oklahoma Medical Research Foundation","isPivotal":true,"enrollment":101,"indication":"Aging, Insulin Sensitivity","completionDate":"2025-03-12"},{"nctId":"NCT00795678","phase":"N/A","title":"Clinical Study to Assess Entry of Chemotherapeutic Agents Into Brain Metastases in Women With Breast Cancer","status":"COMPLETED","sponsor":"Case Comprehensive Cancer Center","isPivotal":false,"enrollment":10,"indication":"Breast Cancer, Metastatic Cancer","completionDate":"2013-04"},{"nctId":"NCT02485158","phase":"NA","title":"A Preliminary Investigation of Individual Differences in Subjective Responses to D-amphetamine, Alcohol, and Delta-9-tetrahydrocannabinol","status":"COMPLETED","sponsor":"University of Chicago","isPivotal":false,"enrollment":28,"indication":"Healthy","completionDate":"2013-12"},{"nctId":"NCT01444651","phase":"Phase 3","title":"Phase 3 Randomized Trial of Tadalafil and Glycemic Traits","status":"COMPLETED","sponsor":"Thomas J. Wang, MD","isPivotal":true,"enrollment":73,"indication":"Cardiovascular Disease, Insulin Resistance","completionDate":"2013-03"},{"nctId":"NCT02390180","phase":"N/A","title":"Sorting of Oral Sensations","status":"COMPLETED","sponsor":"Purdue University","isPivotal":false,"enrollment":107,"indication":"Taste Qualities, Primary Tastes","completionDate":"2015-03"},{"nctId":"NCT02136329","phase":"Phase 1","title":"A Phase I Study to Determine the Pharmacokinetic Profile, Safety and Tolerability of Sildenafil (REVATIO®) in Cardiac Surgery","status":"COMPLETED","sponsor":"University of Leicester","isPivotal":false,"enrollment":36,"indication":"Acute Kidney Injury","completionDate":"2014-12"},{"nctId":"NCT02528461","phase":"N/A","title":"Measuring Inflammation Cells (CD163 and CD206) With the Purpose of Examining Reduction of Fibrosis in the Liver of Chronic Hepatitis C Patients Following Treatment With the Medication Sofosbuvir","status":"COMPLETED","sponsor":"University of Aarhus","isPivotal":false,"enrollment":71,"indication":"Hepatitis C","completionDate":"2020-01"},{"nctId":"NCT02511041","phase":"Phase 1","title":"Immunologic Effects of Supplemental Monosaccharide and Nucleoside Derivatives in Patients With Inherited Disorders of Glycosylation","status":"TERMINATED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","isPivotal":false,"enrollment":2,"indication":"PGM3","completionDate":"2017-01-24"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"MMSL":"11133","NDDF":"000915","UNII":"2XQS08K9WE","CHEBI":"CHEBI:29042","VANDF":"4017760","RXNORM":"4850","UMLSCUI":"C0061414","DRUGBANK_ID":"DB02843","PDB_CHEM_ID":" BGC","PUBCHEM_CID":"65533","SNOMEDCT_US":"111138002","MESH_DESCRIPTOR_UI":"D005947","MESH_SUPPLEMENTAL_RECORD_UI":"C031590"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1653,"therapeuticAreas":["Metabolic"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 Mar","pmid":"41871161","title":"Functional and molecular characterization of Aspergillus fumigatus phosphoglucomutase (Pgm): a potential target for antifungal therapy.","journal":"Journal of medical microbiology"},{"date":"2026 Mar 23","pmid":"41866930","title":"Diet, gut microbiota and urinary metabolite profiles associated with lunularin metabotypes in young Chinese adults.","journal":"Food & function"},{"date":"2026 Mar 20","pmid":"41860213","title":"Endocrine Disruptor 2,7-Dibromocarbazole Disrupts Energy Metabolism and Alters Locomotor Behavior in Juvenile Zebrafish.","journal":"Chemical research in toxicology"},{"date":"2026 Mar 13","pmid":"41846136","title":"Boron fortifies a dual barrier in rice roots: How Casparian strip reinforcement and cell wall remodeling restrict cadmium entry.","journal":"Journal of hazardous materials"},{"date":"2026 May 15","pmid":"41832017","title":"Programmable amylose architectures via α-glucan phosphorylase coupling: From process variables to structure-property map.","journal":"Carbohydrate polymers"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Glucose-1-phosphate is a small molecule drug in the glucose-1-phosphate class, but information on its development, commercial status, and approved indications is not available. As a result, there is limited information on its target, half-life, bioavailability, and generic manufacturers. The mechanism of action of glucose-1-phosphate is not well-documented, but it is believed to work by influencing glucose metabolism. Further research is needed to fully understand its effects and potential applications. Unfortunately, without more information, it is difficult to provide a comprehensive summary of this compound.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}