{"id":"gl-0817","safety":{"commonSideEffects":[{"rate":"null","effect":"Fatigue"},{"rate":"null","effect":"Nausea"},{"rate":"null","effect":"Diarrhea"}]},"_chembl":{"chemblId":"CHEMBL5994951","moleculeType":null,"molecularWeight":"419.40"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It works by blocking the CD47 signal that cancer cells use to evade the immune system, allowing the immune system to recognize and attack cancer cells.","oneSentence":"GL-0817 is an anti-CD47 monoclonal antibody.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T02:38:30.160Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Relapsed or refractory multiple myeloma"}]},"trialDetails":[{"nctId":"NCT02873819","phase":"PHASE2","title":"Safety and Efficacy Study of GL-0817 (With Cyclophosphamide) for the Prevention of Recurrence of Squamous Cell Carcinoma of the Oral Cavity","status":"COMPLETED","sponsor":"Gliknik Inc.","startDate":"2017-03-30","conditions":"Squamous Cell Carcinoma of the Oral Cavity","enrollment":80}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Biropepimut-S"],"phase":"phase_2","status":"active","brandName":"GL-0817","genericName":"GL-0817","companyName":"Gliknik Inc.","companyId":"gliknik-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"GL-0817 is an anti-CD47 monoclonal antibody. Used for Relapsed or refractory multiple myeloma.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}