{"id":"ginsenoside-re","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Insomnia"},{"rate":null,"effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL510095","moleculeType":"Oligosaccharide","molecularWeight":"947.17"},"_dailymed":{"setId":"2d80a71d-5637-4943-98ee-9ef07d916406","title":"GINSENOSIDE RG1 REJUVENATING MOISTURIZING (GLYCERIN) CREAM [CORPORATION SORISO]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Ginsenoside RE acts as an adaptogen, enhancing cellular stress resistance and promoting homeostasis through activation of heat shock proteins and antioxidant defense systems. It exhibits anti-inflammatory properties by inhibiting pro-inflammatory cytokine production and modulating immune cell function. The compound also demonstrates neuroprotective and cardioprotective effects through multiple signaling pathways including MAPK and PI3K/Akt pathways.","oneSentence":"Ginsenoside RE is a natural triterpenoid saponin from ginseng that modulates multiple cellular pathways including stress response, anti-inflammatory, and antioxidant mechanisms.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T04:39:59.616Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Marketed as dietary supplement/traditional medicine for general wellness and stress adaptation"}]},"trialDetails":[{"nctId":"NCT04069715","phase":"PHASE2","title":"The Effect of Farlong® NotoGinseng™ (Ginseng Plus®) on Cholesterol and Blood Pressure","status":"COMPLETED","sponsor":"LongStar HealthPro, Inc. DBA Farlong Pharmaceutical","startDate":"2016-07-20","conditions":"Hyperlipidemias, Hypertension","enrollment":95},{"nctId":"NCT04142151","phase":"NA","title":"Double Randomized and Placebo Controlled Trail of Sanchitongshu Combined Antiplatelet Drug to Prevent Ischemic Stroke","status":"UNKNOWN","sponsor":"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","startDate":"2019-09-01","conditions":"Ischemic Stroke, Antiplatelet Effect","enrollment":60},{"nctId":"NCT00781534","phase":"EARLY_PHASE1","title":"A Clinical Trial of Ginseng in Diabetes","status":"COMPLETED","sponsor":"Washington University School of Medicine","startDate":"2003-09","conditions":"Diabetes","enrollment":19},{"nctId":"NCT02413099","phase":"PHASE4","title":"The Efficacy and Safety of New Herbal Formula (KBMSI-2) in the Treatment of Erectile Dysfunction","status":"COMPLETED","sponsor":"Hyun Jun Park","startDate":"2012-02","conditions":"Erectile Dysfunction","enrollment":44},{"nctId":"NCT02204826","phase":"PHASE4","title":"Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: a Randomized, Placebo-controlled, Double-blind Clinical Study","status":"COMPLETED","sponsor":"Pusan National University Hospital","startDate":"2011-04","conditions":"Male Infertility","enrollment":80},{"nctId":"NCT02975076","phase":"NA","title":"Sanchitongtshu Plus Asprine for Minor Ischemic Stroke or Transient Ischemic Attack: A Randomized Double-blind Study","status":"UNKNOWN","sponsor":"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","startDate":"2016-12","conditions":"Stroke, Acute, Ischemic Attack, Transient","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":458,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"ginsenoside RE","genericName":"ginsenoside RE","companyName":"Washington University School of Medicine","companyId":"washington-university-school-of-medicine","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ginsenoside RE is a natural triterpenoid saponin from ginseng that modulates multiple cellular pathways including stress response, anti-inflammatory, and antioxidant mechanisms. Used for Marketed as dietary supplement/traditional medicine for general wellness and stress adaptation.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}