{"id":"ginkgo","rwe":[{"pmid":"41909050","year":"2026","title":"Rhodiola rosea, Ginkgo biloba, and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders.","finding":"","journal":"Frontiers in nutrition","studyType":"Clinical Study"},{"pmid":"41908799","year":"2025","title":"Ginkgo biloba extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials.","finding":"","journal":"Frontiers in neurology","studyType":"Clinical Study"},{"pmid":"41893342","year":"2026","title":"Functional Analysis of GbFLS1045 Regulating the Metabolism of Flavonoids in Ginkgo biloba L.","finding":"","journal":"Metabolites","studyType":"Clinical Study"},{"pmid":"41893025","year":"2026","title":"A Multi-Axis Framework for Late-Life Alzheimer's Disease Interpretation.","finding":"","journal":"Journal of personalized medicine","studyType":"Clinical Study"},{"pmid":"41882150","year":"2026","title":"Heterologous expression of Ginkgo biloba flavanone 3-hydroxylase acts as a key metabolic switch partitioning flavonoid metabolic flux in transgenic tobacco.","finding":"","journal":"Planta","studyType":"Clinical Study"}],"_fda":{"id":"2786f3a9-d2a7-a945-e063-6294a90a1700","set_id":"05038fb6-033f-4e5f-a476-07e15160a03d","openfda":{"unii":["G580B439YI","5EF0HWI5WU","T7J046YI2B","RN2HC612GY","YHA2XLJ956","VB06AV5US8","1W0775VX6E","91GQH8I5F7","639KR60Q1Q","19FUJ2C58T","Q3P251C5MT","2ZSC17SIJ6","8V4458342X","B93BQX9789","11E6VI8VEG","Q1RGP4UB73","29SUH5R3HU","H6241UJ22B","QBR70R4FBK","ID3Z1X61WY"],"route":["ORAL"],"spl_id":["2786f3a9-d2a7-a945-e063-6294a90a1700"],"brand_name":["Flu-Tone"],"spl_set_id":["05038fb6-033f-4e5f-a476-07e15160a03d"],"package_ndc":["64578-0136-1"],"product_ndc":["64578-0136"],"generic_name":["ANAS BARBARIAE, HEPATIS ET CORDIS EXTRACTUM, AZADIRACHTA INDICA, BAPTISIA TINCTORIA, BRYONIA (ALBA), CROTALUS HORRIDUS, ECHINACEA (ANGUSTIFOLIA), EUPATORIUM PERFOLIATUM, FERRUM PHOSPHORICUM, GELSEMIUM SEMPERVIRENS, GINKGO BILOBA, INFLUENZINUM, MUCOSA NASALIS SUIS, PHYTOLACCA DECANDRA, PINUS SYLVESTRIS, PYROGENIUM, SELENIUM METALLICUM, STILLINGIA SYLVATICA"],"product_type":["HUMAN OTC DRUG"],"substance_name":["AZADIRACHTA INDICA BARK","BAPTISIA TINCTORIA ROOT","BRYONIA ALBA ROOT","CAIRINA MOSCHATA HEART/LIVER AUTOLYSATE","CROTALUS HORRIDUS HORRIDUS VENOM","ECHINACEA ANGUSTIFOLIA","EUPATORIUM PERFOLIATUM FLOWERING TOP","FERRUM PHOSPHORICUM","GELSEMIUM SEMPERVIRENS ROOT","GINKGO","INFLUENZA A VIRUS A/SINGAPORE/GP1908/2015 IVR-180 (H1N1) ANTIGEN (FORMALDEHYDE INACTIVATED)","INFLUENZA A VIRUS A/SINGAPORE/INFIMH-16-0019/2016 NIB-104 (H3N2) ANTIGEN (FORMALDEHYDE INACTIVATED)","INFLUENZA B VIRUS B/MARYLAND/15/2016 ANTIGEN (FORMALDEHYDE INACTIVATED)","INFLUENZA B VIRUS B/PHUKET/3073/2013 ANTIGEN (FORMALDEHYDE INACTIVATED)","PHYTOLACCA AMERICANA ROOT","PINUS SYLVESTRIS LEAFY TWIG","RANCID BEEF","SELENIUM","STILLINGIA SYLVATICA ROOT","SUS SCROFA NASAL MUCOSA"],"manufacturer_name":["Energetix Corporation"],"is_original_packager":[true]},"purpose":["Purpose Temporary relief of flu-like symptoms such as aches, fever, nausea, cough, fatigue."],"version":"7","warnings":["Warnings In case of overdose, get medical help or call a Poison Control Center right away. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children."],"questions":["Distributed by Energetix Corp Dahlonega, GA 30533 Questions? Comments? 800.990.7085 www.energetix.com"],"effective_time":"20250715","active_ingredient":["Active ingredients: 59.1 mL contains 4.34% of Anas barbariae 15C, 30C; Azadirachta 12X; Baptisia 4X; Bryonia 12X; Crotalus hor 15X; Echinacea 4X; Eupatorium perf 30X, 30C; Ferrum phos 12X; Gelsemium 6X; Ginkgo 4X; Influenzinum 30X, 30C; Mucosa nas 9X, 12X, 6C; Phytolacca 4X; Pinus syl 9X; Pyrogenium 30X, 30C; Selenium 12X; Stillingia 4X. Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated."],"inactive_ingredient":["Inactive ingredients Alcohol, Vegetable Glycerin, Purified Water."],"indications_and_usage":["Uses Temporary relief of flu-like symptoms such as aches, fever, nausea, cough, fatigue."],"other_safety_information":["Other information Store at room temperature out of direct sunlight. Do not use if neck wrap is broken or missing. Shake well before use."],"dosage_and_administration":["Take 30 drops orally twice daily or as directed by a healthcare professional. Consult a physician for use in children under 12 years of age or if symptoms worsen or persist."],"spl_product_data_elements":["Flu-Tone Anas Barbariae, Hepatis Et Cordis Extractum, Azadirachta Indica, Baptisia Tinctoria, Bryonia (Alba), Crotalus Horridus, Echinacea (Angustifolia), Eupatorium Perfoliatum, Ferrum Phosphoricum, Gelsemium Sempervirens, Ginkgo Biloba, Influenzinum, Mucosa Nasalis Suis, Phytolacca Decandra, Pinus Sylvestris, Pyrogenium, Selenium Metallicum, Stillingia Sylvatica WATER ALCOHOL GLYCERIN CAIRINA MOSCHATA HEART/LIVER AUTOLYSATE CAIRINA MOSCHATA HEART/LIVER AUTOLYSATE AZADIRACHTA INDICA BARK AZADIRACHTA INDICA BARK BAPTISIA TINCTORIA ROOT BAPTISIA TINCTORIA ROOT BRYONIA ALBA ROOT BRYONIA ALBA ROOT CROTALUS HORRIDUS HORRIDUS VENOM CROTALUS HORRIDUS HORRIDUS VENOM ECHINACEA ANGUSTIFOLIA ECHINACEA ANGUSTIFOLIA EUPATORIUM PERFOLIATUM FLOWERING TOP EUPATORIUM PERFOLIATUM FLOWERING TOP FERRUM PHOSPHORICUM FERROSOFERRIC PHOSPHATE GELSEMIUM SEMPERVIRENS ROOT GELSEMIUM SEMPERVIRENS ROOT GINKGO GINKGO INFLUENZA A VIRUS A/SINGAPORE/GP1908/2015 IVR-180 (H1N1) ANTIGEN (FORMALDEHYDE INACTIVATED) INFLUENZA A VIRUS A/SINGAPORE/GP1908/2015 IVR-180 (H1N1) HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED) INFLUENZA A VIRUS A/SINGAPORE/INFIMH-16-0019/2016 NIB-104 (H3N2) ANTIGEN (FORMALDEHYDE INACTIVATED) INFLUENZA A VIRUS A/SINGAPORE/INFIMH-16-0019/2016 NIB-104 (H3N2) HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED) INFLUENZA B VIRUS B/MARYLAND/15/2016 ANTIGEN (FORMALDEHYDE INACTIVATED) INFLUENZA B VIRUS B/MARYLAND/15/2016 HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED) INFLUENZA B VIRUS B/PHUKET/3073/2013 ANTIGEN (FORMALDEHYDE INACTIVATED) INFLUENZA B VIRUS B/PHUKET/3073/2013 HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED) SUS SCROFA NASAL MUCOSA SUS SCROFA NASAL MUCOSA PHYTOLACCA AMERICANA ROOT PHYTOLACCA AMERICANA ROOT PINUS SYLVESTRIS LEAFY TWIG PINUS SYLVESTRIS LEAFY TWIG RANCID BEEF RANCID BEEF SELENIUM SELENIUM STILLINGIA SYLVATICA ROOT STILLINGIA SYLVATICA ROOT"],"keep_out_of_reach_of_children":["Keep out of reach of children."],"package_label_principal_display_panel":["energetix Flu-Tone Homeopathic Remedy Flu-like symptoms such as aches, fever, nausea, cough, fatigue. 2 fl oz (59.1 mL) / 15% Alcohol Flu-Tone r09-24 03021 Purpose Temporary relief of flu-like symptoms such as aches, fever, nausea, cough, fatigue."]},"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Oral","category":"route"},{"label":"Active","category":"status"},{"label":"flu-like symptoms","category":"indication"},{"label":"Energetix Corporation","category":"company"}],"phase":"marketed","safety":{"boxedWarnings":[],"safetySignals":[{"date":"","signal":"FATIGUE","source":"FDA FAERS","actionTaken":"119 reports"},{"date":"","signal":"HEADACHE","source":"FDA FAERS","actionTaken":"109 reports"},{"date":"","signal":"DIZZINESS","source":"FDA FAERS","actionTaken":"102 reports"},{"date":"","signal":"DRUG INEFFECTIVE","source":"FDA FAERS","actionTaken":"100 reports"},{"date":"","signal":"NAUSEA","source":"FDA FAERS","actionTaken":"99 reports"},{"date":"","signal":"PAIN","source":"FDA FAERS","actionTaken":"87 reports"},{"date":"","signal":"ASTHENIA","source":"FDA FAERS","actionTaken":"73 reports"},{"date":"","signal":"DIARRHOEA","source":"FDA FAERS","actionTaken":"73 reports"},{"date":"","signal":"FALL","source":"FDA FAERS","actionTaken":"70 reports"},{"date":"","signal":"PAIN IN EXTREMITY","source":"FDA FAERS","actionTaken":"69 reports"}]},"trials":[],"aliases":[],"company":"Energetix Corporation","patents":[],"pricing":[],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=GINKGO","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T00:51:05.995666+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T00:51:11.271365+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=GINKGO","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T00:51:11.568020+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T00:51:04.730297+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T00:51:04.730328+00:00"},"safety.safetySignals":{"url":"https://api.fda.gov/drug/event.json","method":"api_direct","source":"FDA FAERS","rawText":"","confidence":1,"sourceType":"fda_faers","retrievedAt":"2026-04-20T00:51:13.259384+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL2108466/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T00:51:12.391749+00:00"}},"allNames":"flu-tone","offLabel":[],"synonyms":["Flu-Tone","AZADIRACHTA INDICA BARK"],"timeline":[],"approvals":[],"brandName":"Flu-Tone","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"","oneSentence":"","technicalDetail":"Ginkgo biloba extract is believed to exert its anti-inflammatory effects through the inhibition of platelet-activating factor (PAF), a potent phospholipid mediator involved in the inflammatory response, thereby modulating the immune system's response to infection."},"commercial":{},"references":[{"id":1,"url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:\"GINKGO\"","fields":["mechanism","indications","adverse_reactions","contraindications","warnings","dosage"],"source":"OpenFDA Label"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=ginkgo","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ginkgo","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-31T10:30:48.310638","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T00:51:14.543154+00:00","fieldsConflicting":1,"overallConfidence":0.8},"biosimilars":[],"competitors":[],"genericName":"ginkgo","indications":{"approved":[{"name":"flu-like symptoms","source":"OpenFDA Label","regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT07220538","phase":"PHASE4","title":"A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment","status":"RECRUITING","sponsor":"Dr. Willmar Schwabe GmbH & Co. KG","startDate":"2025-11-28","conditions":["Ischemic Stroke Hospitalized","Impairment, Cognitive"],"enrollment":400,"completionDate":"2027-12-31"},{"nctId":"NCT07411339","phase":"NA","title":"Ginkgo Active App-Based Exercise Training","status":"NOT_YET_RECRUITING","sponsor":"University of Maryland, Baltimore","startDate":"2026-03-01","conditions":["Healthy Adult Participants","Controlled Hypertension","Controlled Diabetes"],"enrollment":60,"completionDate":"2027-05-01"},{"nctId":"NCT06771128","phase":"NA","title":"Ginkgo Biloba vs Desmopressin in Treatment of Children With Monosymptomatic Nocturnal Enuresis","status":"COMPLETED","sponsor":"Menoufia University","startDate":"2024-11-01","conditions":["Nocturnal Enuresis in Children","Desmopressin","Monosymptomatic Nocturnal Enuresis"],"enrollment":398,"completionDate":"2026-01-01"},{"nctId":"NCT04784234","phase":"NA","title":"Vision Preservation and Restoration Following a 6 Month Trial of GlaucoCetin","status":"TERMINATED","sponsor":"Wills Eye","startDate":"2021-02-01","conditions":["Primary Open Angle Glaucoma"],"enrollment":12,"completionDate":"2022-10-27"},{"nctId":"NCT07287852","phase":"PHASE2","title":"A Pilot Study to Examine the Effect of Egb761 on Plasma Biomarker Levels and on Cognitive Function in Patients With MCI","status":"ENROLLING_BY_INVITATION","sponsor":"Hadassah Medical Organization","startDate":"2024-08-20","conditions":["Alzheimer Disease (AD)","Mild Cognitive Impairment (MCI)"],"enrollment":50,"completionDate":"2026-12"},{"nctId":"NCT07283562","phase":"NA","title":"Gastrodin Acupoint Injection for Sensorineural Hearing Loss With Vertigo","status":"COMPLETED","sponsor":"The First Hospital of Hebei Medical University","startDate":"2023-01-01","conditions":["Sensorineural Hearing Loss","Vertigo"],"enrollment":100,"completionDate":"2025-10-31"},{"nctId":"NCT07247071","phase":"","title":"Modifiable Risk Factors for Non-traumatic Subconjunctival Hemorrhage","status":"COMPLETED","sponsor":"Hallym University Kangnam Sacred Heart Hospital","startDate":"2022-12-22","conditions":["Subconjunctival Hemorrhage"],"enrollment":67,"completionDate":"2024-12-28"},{"nctId":"NCT07236645","phase":"PHASE2","title":"Efficacy and Safety of Ginkgo Biloba Extract EGb761® in Patients With Diabetic Retinopathy","status":"NOT_YET_RECRUITING","sponsor":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","startDate":"2025-11-20","conditions":["Non-proliferative Diabetic Retinopathy (NPDR)"],"enrollment":200,"completionDate":"2028-12-31"},{"nctId":"NCT06813274","phase":"PHASE2","title":"Multicenter RCT of Eye-Brain Imaging in Diabetes Neurovascular Coupling","status":"NOT_YET_RECRUITING","sponsor":"Hejiang Ye","startDate":"2026-01-01","conditions":["Diabetes Mellitus","Diabetic Retinopathy","Cognitive Impairment","Neurovascular Coupling"],"enrollment":160,"completionDate":"2026-12-01"},{"nctId":"NCT05067998","phase":"","title":"The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature","status":"RECRUITING","sponsor":"Faith A. Richardson","startDate":"2025-12-21","conditions":["Anxiety Disorders and Symptoms","Fibromyalgia","Arthritis","Chronic Pain","Hypertension,Essential"],"enrollment":25,"completionDate":"2026-09-17"},{"nctId":"NCT06583941","phase":"NA","title":"Effects of Indena's Virtiva® Plus Ginkgo Biloba Extract on Stress, and Cognitive Performance","status":"COMPLETED","sponsor":"Applied Science & Performance Institute","startDate":"2025-01-10","conditions":["Stress","Mood","Cognitive Change"],"enrollment":60,"completionDate":"2025-04-04"},{"nctId":"NCT07166835","phase":"NA","title":"Exploring the Cognitive Benefits of a Blackcurrant-Based Supplement in Normobaric Hypoxia","status":"NOT_YET_RECRUITING","sponsor":"Leeds Beckett University","startDate":"2025-09-01","conditions":["Cognitive Performance","Executive Function (Cognition)","Working Memory","Hypoxia Induced Cognitive Impairment","Mood"],"enrollment":27,"completionDate":"2027-10-01"},{"nctId":"NCT06759753","phase":"PHASE2","title":"Aleeto in Acute ISchemic Stroke：A RandomISed Controlled Clinical Trial","status":"RECRUITING","sponsor":"Beijing Tiantan Hospital","startDate":"2025-03-21","conditions":["Acute Ischemic Stroke"],"enrollment":192,"completionDate":"2026-01-31"},{"nctId":"NCT07060391","phase":"PHASE3","title":"A Prospective Multicenter RCT Study of Deep Jugular Lymphovenous Anastomosis in the Treatment of Alzheimer's Disease","status":"NOT_YET_RECRUITING","sponsor":"Shanghai Jiao Tong University School of Medicine","startDate":"2025-07-31","conditions":["Alzheimer's Disease"],"enrollment":186,"completionDate":"2027-01-31"},{"nctId":"NCT06989697","phase":"PHASE3","title":"Cilostazol-Ginkgo for Cognitive Function in Elderly Diabetes","status":"RECRUITING","sponsor":"Seoul National University Bundang Hospital","startDate":"2025-01-01","conditions":["Type 2 Diabets Mellitus","Cognitive Ability, General"],"enrollment":80,"completionDate":"2027-06-30"},{"nctId":"NCT05906199","phase":"PHASE4","title":"A Study to Compare the Effects of Improving the Carotid Artery Intima Media Thickness and Changing Lipid Levels by Cilostazol/Ginkgo Leaf Extract and Aspirin in Diabetic Peripheral Angiopathy.","status":"COMPLETED","sponsor":"SK Chemicals Co., Ltd.","startDate":"2021-07-28","conditions":["Diabetic Peripheral Angiopathy"],"enrollment":105,"completionDate":"2023-12-13"},{"nctId":"NCT06861426","phase":"","title":"Effectiveness of Ginkgo Diterpene Lactone Meglumine in Acute Ischemic Stroke","status":"NOT_YET_RECRUITING","sponsor":"Ying Gao","startDate":"2025-03-01","conditions":["Acute Ischemic Stroke"],"enrollment":4460,"completionDate":"2025-12-31"},{"nctId":"NCT05591144","phase":"NA","title":"Short-term Oral Prednisone for Acute Subjective Tinnitus","status":"COMPLETED","sponsor":"Eye & ENT Hospital of Fudan University","startDate":"2022-10-30","conditions":["Tinnitus, Subjective"],"enrollment":146,"completionDate":"2024-02-03"},{"nctId":"NCT06704334","phase":"PHASE4","title":"The Study of Ginkgo Leaf Dropping Pills and Huperzine a Injection Combined with Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain Injury","status":"RECRUITING","sponsor":"Wanbangde Pharmaceutical Group Co., LTD","startDate":"2024-04-01","conditions":["Cognitive Impairment After Brain Injury"],"enrollment":50,"completionDate":"2026-12-31"},{"nctId":"NCT06689644","phase":"NA","title":"Effect of a Plant Based Nootropic on Perceptual Decision Making.","status":"COMPLETED","sponsor":"University of Leeds","startDate":"2023-10-23","conditions":["Cognitive Enhancement"],"enrollment":37,"completionDate":"2024-06-01"},{"nctId":"NCT06495476","phase":"PHASE4","title":"Study on Ginkgo Biolba Extract Fifty and Mild Cognitive Impairment Associated With CSVD","status":"NOT_YET_RECRUITING","sponsor":"Beijing Tiantan Hospital","startDate":"2024-09-01","conditions":["Mild Cognitive Impairment"],"enrollment":144,"completionDate":"2026-06-30"},{"nctId":"NCT04846179","phase":"PHASE4","title":"To Evaluate the Effect of Ginkgo Biloba Extract on Optic Nerve Head Perfusion Examined Using OCTA","status":"COMPLETED","sponsor":"Nova Scotia Health Authority","startDate":"2021-05-01","conditions":["Glaucoma"],"enrollment":15,"completionDate":"2024-03-31"},{"nctId":"NCT06309914","phase":"NA","title":"The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States","status":"COMPLETED","sponsor":"Applied Science & Performance Institute","startDate":"2024-02-21","conditions":["Mental Processes","Cognitive Change","Mood Change"],"enrollment":76,"completionDate":"2024-07-08"},{"nctId":"NCT06496087","phase":"NA","title":"Evaluation of DEPREXIL in Patients With Clinical Depression Through Psychological and Neuroendocrine Assessment","status":"COMPLETED","sponsor":"Catalysis SL","startDate":"2022-11-01","conditions":["Depression","Post-COVID-19 Syndrome","Depression Mild","Depression Moderate"],"enrollment":100,"completionDate":"2024-04-15"},{"nctId":"NCT06403787","phase":"PHASE2,PHASE3","title":"Effect of Aerobic Training and Ginkgo Biloba on Lipids Levels in HIV-positive Patients Undergoing Antiretroviral Treatment","status":"COMPLETED","sponsor":"University of Guadalajara","startDate":"2022-05-01","conditions":["Human Immunodeficiency Virus"],"enrollment":28,"completionDate":"2024-04-01"},{"nctId":"NCT00276341","phase":"PHASE3","title":"Study on the Effectiveness of EGb 761® vs Placebo Used for Cognitive Impairment in Patients With Multiple Sclerosis","status":"COMPLETED","sponsor":"Ipsen","startDate":"2003-08-26","conditions":["Multiple Sclerosis, Relapsing-Remitting"],"enrollment":47,"completionDate":"2005-12-08"},{"nctId":"NCT06140888","phase":"NA","title":"Effect of Ginkgo Biloba Extract on Cognitive Function in Acute Ischemic Stroke","status":"NOT_YET_RECRUITING","sponsor":"Yi Yang","startDate":"2024-03-15","conditions":["Acute Ischemic Stroke"],"enrollment":356,"completionDate":"2027-04-01"},{"nctId":"NCT06274242","phase":"NA","title":"Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults","status":"UNKNOWN","sponsor":"Mahidol University","startDate":"2023-03-10","conditions":["Constipation"],"enrollment":98,"completionDate":"2024-04-19"},{"nctId":"NCT04685005","phase":"NA","title":"\"WakeUp\" for Vigilance Following Lunch","status":"COMPLETED","sponsor":"Carmel Medical Center","startDate":"2018-11-01","conditions":["Fatigue"],"enrollment":30,"completionDate":"2019-12-31"},{"nctId":"NCT06224582","phase":"NA","title":"Yinxingmihuan Oral Solution in Treatment of Chest Pain After PCI","status":"COMPLETED","sponsor":"China National Center for Cardiovascular Diseases","startDate":"2020-12-30","conditions":["Chronic Stable Angina"],"enrollment":320,"completionDate":"2023-12-25"},{"nctId":"NCT05300594","phase":"NA","title":"Effect of Audistim® Day/Night on Hearing Comfort and Patient Quality of Life of Patients With Chronic Tinnitus.","status":"COMPLETED","sponsor":"CEN Biotech","startDate":"2022-03-01","conditions":["Tinnitus"],"enrollment":110,"completionDate":"2023-06-05"},{"nctId":"NCT06124703","phase":"NA","title":"Different Dosing Regimens of STOP-AST","status":"UNKNOWN","sponsor":"Eye & ENT Hospital of Fudan University","startDate":"2023-11-10","conditions":["Hearing Loss","Tinnitus","Sensorineural Hearing Loss"],"enrollment":162,"completionDate":"2024-11-30"},{"nctId":"NCT05855863","phase":"PHASE4","title":"Clinical Study of GKT in Diabetes Related Dementia","status":"NOT_YET_RECRUITING","sponsor":"Shanghai 10th People's Hospital","startDate":"2023-12-01","conditions":["Dementia"],"enrollment":370,"completionDate":"2026-06-30"},{"nctId":"NCT05531942","phase":"PHASE2,PHASE3","title":"Antiplatelet Effect of Ginkgo Diterpene Lactone Meglumine Injection in Acute Ischemic Stroke","status":"UNKNOWN","sponsor":"Shanghai Yueyang Integrated Medicine Hospital","startDate":"2021-01-01","conditions":["Ischemic Stroke"],"enrollment":70,"completionDate":"2023-11-01"},{"nctId":"NCT00500500","phase":"PHASE2","title":"Effect of EGb 761® on Patients With Mild to Moderate Alzheimer's Disease","status":"TERMINATED","sponsor":"Ipsen","startDate":"2005-07","conditions":["Alzheimer Disease"],"enrollment":40,"completionDate":"2008-04"},{"nctId":"NCT05591885","phase":"NA","title":"Nutrilite Memory Builder on the Improvement of Cognitive Function","status":"UNKNOWN","sponsor":"Amway (China) R&D Center","startDate":"2022-10-24","conditions":["Cognitive Function"],"enrollment":100,"completionDate":"2023-05-31"},{"nctId":"NCT02526225","phase":"PHASE2","title":"A Safety and Effective Study of Ginkgolides Diterpene Lactone Meglumine Injection in the Treatment of Ischemic Stroke.","status":"COMPLETED","sponsor":"Beijing Tiantan Hospital","startDate":"2016-02-01","conditions":["Ischemic Stroke"],"enrollment":3452,"completionDate":"2019-08-31"},{"nctId":"NCT05594355","phase":"PHASE4","title":"Effect of Treatment With EGb 761(r) on Blood Markers of Inflammation and Oxidative Stress in Patients With MCI","status":"UNKNOWN","sponsor":"Fundació ACE Institut Català de Neurociències Aplicades","startDate":"2021-04-16","conditions":["Mild Cognitive Impairment (MCI)"],"enrollment":100,"completionDate":"2023-12"},{"nctId":"NCT04499157","phase":"NA","title":"Effect of MEMOPTIC on Visual Field of Patients Followed for a Chronic Open-angle Glaucoma","status":"UNKNOWN","sponsor":"Centre Hospitalier Universitaire, Amiens","startDate":"2020-08-01","conditions":["Open-angle Glaucoma","Visual Field"],"enrollment":100,"completionDate":"2023-08"},{"nctId":"NCT04121728","phase":"NA","title":"Modulation of Attention in Event Related Potential (ERPs) as a Marker of Early Cognitive Decline by Ginkgo Biloba","status":"UNKNOWN","sponsor":"Jean-François Démonet","startDate":"2019-09-09","conditions":["Subjective Cognitive Decline","Cognitive Performance","Functional Capacity","Age-related Cognitive Decline"],"enrollment":16,"completionDate":"2024-05-31"},{"nctId":"NCT05663307","phase":"PHASE2,PHASE3","title":"The Effect of Ginkgolide on Clinical Improvement of Patients With Acute Ischemic Stroke","status":"UNKNOWN","sponsor":"Shanghai Yueyang Integrated Medicine Hospital","startDate":"2021-01-01","conditions":["Ischemic Stroke, Acute"],"enrollment":80,"completionDate":"2023-12-01"},{"nctId":"NCT04525144","phase":"PHASE2","title":"EGb 761 in the Syndrome of MCI With Concomitant CVD","status":"RECRUITING","sponsor":"National Neuroscience Institute","startDate":"2020-10-26","conditions":["Mild Cognitive Impairment","Cerebrovascular Disease"],"enrollment":134,"completionDate":"2026-11"},{"nctId":"NCT04448535","phase":"NA","title":"Effects of Ginkgo (Gingko Biloba) on Retinal and Choroidal Ocular Tissue","status":"COMPLETED","sponsor":"State University of New York College of Optometry","startDate":"2021-01-01","conditions":["Healthy"],"enrollment":20,"completionDate":"2022-08-03"},{"nctId":"NCT05398874","phase":"NA","title":"Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Knee Osteoarthritis","status":"COMPLETED","sponsor":"Kufa University","startDate":"2021-11-01","conditions":["Knee Osteoarthritis"],"enrollment":60,"completionDate":"2022-08-01"},{"nctId":"NCT05258123","phase":"NA","title":"Ginkgo Biloba Extract in the Treatment of Schizophrenia","status":"COMPLETED","sponsor":"Beijing HuiLongGuan Hospital","startDate":"2017-05-15","conditions":["Schizophrenia"],"enrollment":100,"completionDate":"2018-08-15"},{"nctId":"NCT02350595","phase":"NA","title":"A Study on the Possible Health Effects of Lean Fish and Fatty Fish Intake in Overweight or Obese Adults","status":"COMPLETED","sponsor":"University of Bergen","startDate":"2011-08","conditions":["Overweight","Obesity"],"enrollment":76,"completionDate":"2012-12"},{"nctId":"NCT04492241","phase":"NA","title":"Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution for the Treatment of Motoric Cognitive Risk Syndrome","status":"UNKNOWN","sponsor":"Beijing Tiantan Hospital","startDate":"2021-07-05","conditions":["Motoric Cognitive Risk Syndrome","Mild Cognitive Impairment","Aging","Locomotive Syndrome"],"enrollment":800,"completionDate":"2024-12-31"},{"nctId":"NCT00070161","phase":"PHASE2","title":"Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor","status":"COMPLETED","sponsor":"Wake Forest University Health Sciences","startDate":"2001-07-01","conditions":["Brain and Central Nervous System Tumors","Radiation Toxicity"],"enrollment":68,"completionDate":"2012-08-01"},{"nctId":"NCT05002036","phase":"PHASE4","title":"Management of Dry Eye Disease After Cataract Surgery With Topical Hyaluronic Acid and Gingko Biloba","status":"COMPLETED","sponsor":"University of Milan","startDate":"2021-02-01","conditions":["Dry Eye Syndromes"],"enrollment":40,"completionDate":"2021-05-01"},{"nctId":"NCT02984813","phase":"PHASE1","title":"Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic Retinopathy","status":"TERMINATED","sponsor":"The New York Eye & Ear Infirmary","startDate":"2016-04-15","conditions":["Open-angle Glaucoma","Diabetic Retinopathy"],"enrollment":21,"completionDate":"2017-01-15"},{"nctId":"NCT04149639","phase":"NA","title":"A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline","status":"COMPLETED","sponsor":"LifeSeasons Inc.","startDate":"2019-11-08","conditions":["Healthy"],"enrollment":40,"completionDate":"2020-07-07"},{"nctId":"NCT01637168","phase":"PHASE3","title":"Comparison of the Panax Ginseng + Associations to Ginkgo Biloba in the Treatment of Cognitive Function Disorders","status":"WITHDRAWN","sponsor":"EMS","startDate":"","conditions":["Memory Deficit"],"enrollment":0,"completionDate":""},{"nctId":"NCT01246804","phase":"PHASE1","title":"The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)","status":"COMPLETED","sponsor":"Radboud University Medical Center","startDate":"2010-11","conditions":["HIV Infections","Depression","Mild Cognitive Impairment"],"enrollment":18,"completionDate":"2011-05"},{"nctId":"NCT04529148","phase":"PHASE4","title":"The Efficacy and Safety of Ginkgo Biloba Dropping Pills in the Treatment of Coronary Heart Disease With Stable Angina Pectoris and Depression","status":"UNKNOWN","sponsor":"Wanbangde Pharmaceutical Group Co., LTD","startDate":"2020-09-20","conditions":["Stable Angina Pectoris Associated With Depression"],"enrollment":72,"completionDate":"2022-09-20"},{"nctId":"NCT00824512","phase":"PHASE2","title":"Efficacy of EGb761 in Patients Suffering From Friedreich Ataxia","status":"COMPLETED","sponsor":"Ipsen","startDate":"2008-06","conditions":["Friedreich Ataxia"],"enrollment":22,"completionDate":"2011-10"},{"nctId":"NCT04334564","phase":"NA","title":"Effect of Ginkgo Biloba Capsule on Visual Function of Primary Open-angle Glaucoma With Blood Stasis Syndrome","status":"UNKNOWN","sponsor":"Zhongshan Ophthalmic Center, Sun Yat-sen University","startDate":"2015-04-28","conditions":["Primary Open Angle Glaucoma","Drug Effect"],"enrollment":512,"completionDate":"2020-11-30"},{"nctId":"NCT02321475","phase":"","title":"EGb 761® (Tanakan®) Effectiveness in the Treatment of Patients of Middle Age and Younger With Psycho-emotional Symptoms, Added to Cognitive Disorders","status":"COMPLETED","sponsor":"Ipsen","startDate":"2014-06","conditions":["Cognitive Disorders"],"enrollment":54,"completionDate":"2015-04"},{"nctId":"NCT03482063","phase":"PHASE2","title":"The Effects of 12 Weeks Supplementation With a B-vitamin and Herbal Supplement on Neurocognitive Function and Mood","status":"COMPLETED","sponsor":"Swisse Wellness Pty Ltd","startDate":"2018-06-18","conditions":["Neurocognitive Function","Mood"],"enrollment":141,"completionDate":"2020-01-09"},{"nctId":"NCT03761992","phase":"NA","title":"Measurement of the Effect of Gingko Biloba Extract on Ocular and Nailfold Blood-flow in NTG","status":"UNKNOWN","sponsor":"Robert Ritch, MD, LLC.","startDate":"2018-11-19","conditions":["Normal Tension Glaucoma"],"enrollment":40,"completionDate":"2020-12"},{"nctId":"NCT03842514","phase":"NA","title":"Food Additives - Do Processed Diets Impact on Gut and Metabolic Health","status":"COMPLETED","sponsor":"University of Aberdeen","startDate":"2019-05-01","conditions":["Gut Health","Metabolic Health"],"enrollment":20,"completionDate":"2020-03-04"},{"nctId":"NCT04192656","phase":"PHASE4","title":"The Effect of PAP on ISSHL Comorbided With OSA","status":"RECRUITING","sponsor":"Beijing Tsinghua Chang Gung Hospital","startDate":"2019-11-01","conditions":["Sudden Hearing Loss","Obstructive Sleep Apnea"],"enrollment":102,"completionDate":"2029-12"},{"nctId":"NCT03295903","phase":"EARLY_PHASE1","title":"Cannabinoid Supplementation on Vascular and Cognitive Function","status":"UNKNOWN","sponsor":"University of British Columbia","startDate":"2018-01-01","conditions":["Diet Modification"],"enrollment":24,"completionDate":"2021-10-01"},{"nctId":"NCT02882438","phase":"PHASE1","title":"Glucosamine Sulphate and Ginkgo Biloba as Antifungal Activity for Treating Tinea Pedis","status":"UNKNOWN","sponsor":"Ahmed A. H. Abdellatif","startDate":"2016-01","conditions":["Foot Infection Tinea Pedis"],"enrollment":30,"completionDate":"2022-10"},{"nctId":"NCT03318276","phase":"PHASE3","title":"Clinical Trial to Evaluate Efficacy and Safety of SID142 in Patients With Chronic Artery Occlusive Disease","status":"COMPLETED","sponsor":"SK Chemicals Co., Ltd.","startDate":"2017-02-20","conditions":["Peripheral Arterial Disease"],"enrollment":170,"completionDate":"2018-10-15"},{"nctId":"NCT03090516","phase":"PHASE2,PHASE3","title":"Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Alzheimer's Disease","status":"UNKNOWN","sponsor":"The First Affiliated Hospital with Nanjing Medical University","startDate":"2016-08-10","conditions":["Alzheimer's"],"enrollment":240,"completionDate":"2020-03-10"},{"nctId":"NCT01536210","phase":"PHASE3","title":"Efficacy and Safety Study of Combination of Ginkgo Extract and Ginseng Extract in Children With ADHD(Attention Deficit Hyperactivity Disorder)","status":"COMPLETED","sponsor":"Yuyu Pharma, Inc.","startDate":"2011-12","conditions":["Mental Disorders"],"enrollment":144,"completionDate":"2012-12"},{"nctId":"NCT01201187","phase":"PHASE3","title":"Efficacy and Safety Study of Combination of Ginkgo Extract and Ginseng Extract(YY-162)in Children With ADHD","status":"COMPLETED","sponsor":"Yuyu Pharma, Inc.","startDate":"2010-03","conditions":["Mental Disorders"],"enrollment":144,"completionDate":"2011-04"},{"nctId":"NCT00814346","phase":"PHASE2","title":"Effect of EGb761® on Brain Glucose Metabolism in Three Groups of Elderly Defined by Cognitive Functions","status":"COMPLETED","sponsor":"Ipsen","startDate":"2008-10","conditions":["Alzheimer's Disease","Cognitive Impairment"],"enrollment":49,"completionDate":"2012-07"},{"nctId":"NCT03228550","phase":"PHASE2","title":"Omega-3 Fatty Acids and Exercise on Mobility and Cognition in Older Women","status":"COMPLETED","sponsor":"Bournemouth University","startDate":"2017-02-26","conditions":["Aging","Cognitive Decline"],"enrollment":60,"completionDate":"2018-12-31"},{"nctId":"NCT00276510","phase":"PHASE4","title":"A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory Complaints","status":"COMPLETED","sponsor":"Ipsen","startDate":"2002-02","conditions":["Memory Disorders, Age-Related","Retention Disorders, Cognitive"],"enrollment":2878,"completionDate":"2009-11"},{"nctId":"NCT02098330","phase":"PHASE3","title":"The Efficacy of Steroid Therapy in Vestibular Neuritis","status":"COMPLETED","sponsor":"Asan Medical Center","startDate":"2014-03","conditions":["Vestibular Neuritis"],"enrollment":40,"completionDate":"2015-06"},{"nctId":"NCT00276380","phase":"PHASE3","title":"A Study on the Use of Tanakan® for Recovery of Neurological Impairment Following Ischaemic Stroke","status":"COMPLETED","sponsor":"Ipsen","startDate":"2003-02","conditions":["Stroke, Acute","Neurological Impairment"],"enrollment":204,"completionDate":"2009-03"},{"nctId":"NCT03772418","phase":"PHASE1","title":"Topical Preparation of Pomegranate and Ginkgo Biloba for Anti-aging Activities","status":"UNKNOWN","sponsor":"Ahmed A. H. Abdellatif","startDate":"2018-05-18","conditions":["Skin and Subcutaneous Tissue Disorders"],"enrollment":30,"completionDate":"2020-02-28"},{"nctId":"NCT03216681","phase":"","title":"Hoat Huyet Nhat Nhat Versus Tanakan for Treatment of Symptoms Related to the Insufficient Blood Supply to the Brain","status":"COMPLETED","sponsor":"Nhat Nhat Pharmaceutical Company","startDate":"2017-07-01","conditions":["Insufficient Blood Supply to the Brain"],"enrollment":750,"completionDate":"2018-04-30"},{"nctId":"NCT02982603","phase":"PHASE4","title":"Efficacy and Safety of Qinggongshoutao Bolus in aMnestic Mild Cognitive Impairment","status":"COMPLETED","sponsor":"Dongzhimen Hospital, Beijing","startDate":"2015-05","conditions":["Mild Cognitive Impairment","Herbal Medicine Allergy"],"enrollment":350,"completionDate":"2017-12"},{"nctId":"NCT00070954","phase":"PHASE1,PHASE2","title":"Ginkgo Biloba to Improve Short-Term Memory Losses Associated With Electroconvulsive Therapy (ECT)","status":"TERMINATED","sponsor":"Medical University of South Carolina","startDate":"2003-02","conditions":["Memory, Short-Term"],"enrollment":50,"completionDate":"2005-03"},{"nctId":"NCT03425045","phase":"NA","title":"Repetitive Transcranial Magnetic Stimulation for Chronic Subjective Tinnitus","status":"COMPLETED","sponsor":"University Hospital Ostrava","startDate":"2015-03-01","conditions":["Tinnitus, Subjective"],"enrollment":40,"completionDate":"2018-03-31"},{"nctId":"NCT03542721","phase":"PHASE4","title":"Effect of DA-5515 (Circulan® Soft Cap.) in Patients With Chronic Fatigue Symptoms Due to Impaired Blood Circulation","status":"UNKNOWN","sponsor":"Dong-A Pharmaceutical","startDate":"2018-01-17","conditions":["Fatigue Symptom"],"enrollment":204,"completionDate":"2019-12"},{"nctId":"NCT03125551","phase":"NA","title":"ROTEM and Dietary Supplements","status":"WITHDRAWN","sponsor":"University of Pretoria","startDate":"2017-06","conditions":["Dietary Supplements","Bleeding Tendency; Due to Coagulation Defect"],"enrollment":0,"completionDate":"2017-08"},{"nctId":"NCT02130908","phase":"NA","title":"A Study on the Possible Health Effects of Lean Fish, Fatty Fish and Lean Meat Intake in Non-obese Adults","status":"COMPLETED","sponsor":"University of Bergen","startDate":"2011-03","conditions":["Metabolic Disorders","Obesity"],"enrollment":45,"completionDate":"2015-07"},{"nctId":"NCT03483779","phase":"PHASE4","title":"Comparing Ginkgo Biloba Pills and Placebo in the Treatment of Coronary Heart Disease With Impaired Glucose Regulation","status":"UNKNOWN","sponsor":"Xiyuan Hospital of China Academy of Chinese Medical Sciences","startDate":"2018-04-25","conditions":["Randomized Controlled Trial","Ginkgo Biloba Extract"],"enrollment":12,"completionDate":"2021-07-30"},{"nctId":"NCT03475823","phase":"NA","title":"Cognitive and Blood Flow Effects of Mountain Tea","status":"COMPLETED","sponsor":"Northumbria University","startDate":"2017-02-17","conditions":["Cognitive Change","Affect","Blood Pressure","Neuroimaging"],"enrollment":155,"completionDate":"2017-09-18"},{"nctId":"NCT02604381","phase":"PHASE2","title":"A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee.","status":"COMPLETED","sponsor":"KGK Science Inc.","startDate":"2015-11","conditions":["Osteoarthritis of the Knee"],"enrollment":200,"completionDate":"2017-06-19"},{"nctId":"NCT03219645","phase":"PHASE2,PHASE3","title":"Ginkgo Diterpene Lactone Meglumine Injection on Platelet Reactivity in Acute Ischemic Stroke","status":"UNKNOWN","sponsor":"RenJi Hospital","startDate":"2017-07-15","conditions":["Ischemic Stroke"],"enrollment":40,"completionDate":"2017-12-31"},{"nctId":"NCT00251238","phase":"PHASE2","title":"Efficacy and Tolerability of Ginkgo Biloba Extract in Patients With Raynaud´s Phenomenon","status":"COMPLETED","sponsor":"VSM Geneesmiddelen b.v.","startDate":"2005-11","conditions":["Raynaud Disease"],"enrollment":41,"completionDate":"2006-04"},{"nctId":"NCT02133989","phase":"PHASE3","title":"Clopidogrel Resistance and Embolism in Carotid Artery Stenting","status":"UNKNOWN","sponsor":"Samsung Medical Center","startDate":"2014-06","conditions":["Carotid Stenosis"],"enrollment":86,"completionDate":"2017-12"},{"nctId":"NCT02298426","phase":"NA","title":"Body Constitution Classification Based Comprehensive Health Management Intervention on Obese Population","status":"COMPLETED","sponsor":"Hai-Jun Wang","startDate":"2014-04","conditions":["Overweight","Obesity"],"enrollment":1452,"completionDate":"2015-10"},{"nctId":"NCT03004508","phase":"PHASE2","title":"Safety of Ginkgo Biloba Leaf Extract","status":"UNKNOWN","sponsor":"IRCCS San Raffaele","startDate":"2015-07","conditions":["Healthy"],"enrollment":66,"completionDate":"2017-01"},{"nctId":"NCT01663467","phase":"NA","title":"Efficacy of Internet and Smartphone Application-delivered Tinnitus Retraining Therapy","status":"WITHDRAWN","sponsor":"Seoul National University Hospital","startDate":"2014-09","conditions":["Tinnitus"],"enrollment":0,"completionDate":"2016-09"},{"nctId":"NCT01524380","phase":"NA","title":"Ginkgo Biloba Extract for Schizophrenia","status":"COMPLETED","sponsor":"Beijing HuiLongGuan Hospital","startDate":"2011-09","conditions":["Schizophrenia"],"enrollment":124,"completionDate":"2013-08"},{"nctId":"NCT00046891","phase":"PHASE3","title":"EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer","status":"COMPLETED","sponsor":"Alliance for Clinical Trials in Oncology","startDate":"2002-12","conditions":["Breast Cancer","Neurotoxicity"],"enrollment":226,"completionDate":"2015-04"},{"nctId":"NCT02425436","phase":"PHASE2","title":"Role of Ginkgo Biloba Extract in IUGR","status":"COMPLETED","sponsor":"Assiut University","startDate":"2014-05","conditions":["Intrauterine Growth Restriction (IUGR)"],"enrollment":226,"completionDate":"2015-12"},{"nctId":"NCT01895400","phase":"PHASE3","title":"Effect of Renexin Tablet in Patients With Recurrent Vestibulopathy","status":"TERMINATED","sponsor":"Jong Woo Chung","startDate":"2013-07","conditions":["Recurrent Vestibulopathy"],"enrollment":26,"completionDate":"2015-12"},{"nctId":"NCT01046292","phase":"PHASE4","title":"Effect of Ginkgo Biloba Special Extract LI 1370 on Dual-tasking in Patients With MCI","status":"COMPLETED","sponsor":"University Hospital, Basel, Switzerland","startDate":"2010-01","conditions":["Mild Cognitive Impairment"],"enrollment":50,"completionDate":"2015-10"},{"nctId":"NCT00446485","phase":"PHASE4","title":"Efficacy and Safety of Ginkgo Biloba Extract in Mild Cognitive Impairment and Cerebrovascular Insufficiency","status":"COMPLETED","sponsor":"Milsing d.o.o.","startDate":"2007-05","conditions":["Mild Cognitive Impairment","Cerebrovascular Insufficiency"],"enrollment":90,"completionDate":"2010-04"},{"nctId":"NCT02465749","phase":"EARLY_PHASE1","title":"Clinical Trials of Continuous Oxygen Therapy Combined With Blue Light Deprivation in the Treatment of Retinitis Pigmentosa","status":"UNKNOWN","sponsor":"Sun Yat-sen University","startDate":"2015-05","conditions":["Retinitis Pigmentosa"],"enrollment":404,"completionDate":"2025-06"},{"nctId":"NCT01364311","phase":"NA","title":"Treatment of Dry Eye With Supplements","status":"WITHDRAWN","sponsor":"Medical University of Vienna","startDate":"2011-07","conditions":["Dry Eye Syndromes"],"enrollment":0,"completionDate":"2014-11"},{"nctId":"NCT02386852","phase":"EARLY_PHASE1","title":"Ginseng and Ginkgo Biloba Effects on Cognition as Modulated by Cardiovascular Reactivity","status":"COMPLETED","sponsor":"Sunway University","startDate":"2014-03","conditions":["Blood Pressure","Cognition"],"enrollment":48,"completionDate":"2014-11"},{"nctId":"NCT02376114","phase":"PHASE2","title":"Ginkgo Biloba and Ocular Blood Flow in Primary Open-angle Glaucoma","status":"COMPLETED","sponsor":"Maisonneuve-Rosemont Hospital","startDate":"2011-08","conditions":["Glaucoma, Open-Angle"],"enrollment":19,"completionDate":"2014-02"},{"nctId":"NCT01768429","phase":"NA","title":"The Effect of n-3 Fatty Acids and Fish on Glucose and Lipid Metabolism in Subjects With Impaired Glucose Metabolism","status":"COMPLETED","sponsor":"University of Eastern Finland","startDate":"2012-10","conditions":["Hyperglycemia"],"enrollment":79,"completionDate":""}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{"route":"Oral"},"crossReferences":{"UNII":"G580B439YI","SPL_ID":"2786f3a9-d2a7-a945-e063-6294a90a1700","chemblId":"CHEMBL2108466"},"formularyStatus":[],"_enricherVersion":"v2-openfda","developmentCodes":[],"ownershipHistory":[{"period":"","companyName":"Energetix Corporation","relationship":"Original Developer"}],"publicationCount":5712,"therapeuticAreas":["Hematology"],"biosimilarFilings":[],"originalDeveloper":"Energetix Corporation","recentPublications":[{"date":"2026","pmid":"41909050","title":"Rhodiola rosea, Ginkgo biloba, and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders.","journal":"Frontiers in nutrition"},{"date":"2025","pmid":"41908799","title":"Ginkgo biloba extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials.","journal":"Frontiers in neurology"},{"date":"2026 Mar 13","pmid":"41893342","title":"Functional Analysis of GbFLS1045 Regulating the Metabolism of Flavonoids in Ginkgo biloba L.","journal":"Metabolites"},{"date":"2026 Mar 10","pmid":"41893025","title":"A Multi-Axis Framework for Late-Life Alzheimer's Disease Interpretation.","journal":"Journal of personalized medicine"},{"date":"2026 Mar 26","pmid":"41882150","title":"Heterologous expression of Ginkgo biloba flavanone 3-hydroxylase acts as a key metabolic switch partitioning flavonoid metabolic flux in transgenic tobacco.","journal":"Planta"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"withdrawn","companyName":"Energetix Corporation","companyId":"energetix-corporation","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"","enrichmentLevel":3,"visitCount":0,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"trialStats":{"total":3,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T00:51:14.543154+00:00","fieldsConflicting":1,"overallConfidence":0.8},"verificationStatus":"partial","dataCompleteness":{"mechanism":false,"indications":true,"safety":false,"trials":true,"score":2}}