{"id":"gh21-capsule","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Injection site reaction"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"}]},"_chembl":{"chemblId":"CHEMBL206253","moleculeType":"Small molecule","molecularWeight":"578.60"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"GH21 Capsule works by mimicking the action of natural growth hormone in the body, stimulating growth and development in children with growth hormone deficiency. It is administered via injection and has a rapid onset of action.","oneSentence":"GH21 Capsule is a growth hormone analogue used to treat growth hormone deficiency.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T02:38:14.132Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Growth hormone deficiency in children"}]},"trialDetails":[{"nctId":"NCT07446725","phase":"PHASE1, PHASE2","title":"A Study to Evaluate Safety, PK and Efficacy of GH55 in Combination With GH21 in Patients With Solid Tumors","status":"NOT_YET_RECRUITING","sponsor":"Suzhou Genhouse Bio Co., Ltd.","startDate":"2026-02-24","conditions":"Advanced Solid Tumor Cancer","enrollment":152},{"nctId":"NCT07318649","phase":"PHASE2","title":"Phase 2 Clinical Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of GH21 Capsules Combined With D-1553 Tablets in Subjects With Locally Advanced or Metastatic Solid Tumors With the KRASG12C Mutation","status":"NOT_YET_RECRUITING","sponsor":"Suzhou Genhouse Bio Co., Ltd.","startDate":"2025-12-30","conditions":"Locally Advanced or Metastatic Solid Tumors","enrollment":120},{"nctId":"NCT05183243","phase":"PHASE1","title":"GH21 Capsules for Advanced Solid Tumors: A Study on Safety and Early Results","status":"UNKNOWN","sponsor":"Suzhou Genhouse Bio Co., Ltd.","startDate":"2022-02-20","conditions":"Advanced Solid Tumor, Non-Small Cell Lung Cancer, Pancreatic Cancer","enrollment":68},{"nctId":"NCT06435455","phase":"PHASE1, PHASE2","title":"GH21 Combined With D-1553 in KRAS G12C Mutant Advanced Solid Tumors","status":"NOT_YET_RECRUITING","sponsor":"Suzhou Genhouse Bio Co., Ltd.","startDate":"2024-07-01","conditions":"Locally Advanced or Metastatic Solid Tumors Harboring KRAS G12C Mutation","enrollment":126},{"nctId":"NCT06306456","phase":"PHASE1, PHASE2","title":"A Phase Ib/II Clinical Study of GH21 Capsules Combined With Osimertinib Mesylate Tablets in Patients With NSCLC","status":"RECRUITING","sponsor":"Suzhou Genhouse Bio Co., Ltd.","startDate":"2024-03-05","conditions":"Non-Small Cell Lung Cancer With EGFR Mutation","enrollment":94}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"GH21 Capsule","genericName":"GH21 Capsule","companyName":"Suzhou Genhouse Bio Co., Ltd.","companyId":"suzhou-genhouse-bio-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"GH21 Capsule is a growth hormone analogue used to treat growth hormone deficiency. Used for Growth hormone deficiency in children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}