{"id":"gerepo","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypertension"},{"rate":null,"effect":"Thrombotic events"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Injection site reactions"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"GerEPO functions as an erythropoiesis-stimulating agent (ESA) that mimics the action of endogenous erythropoietin, promoting the proliferation and differentiation of erythroid progenitor cells in the bone marrow. This leads to increased hemoglobin and red blood cell production, addressing anemia in patients with chronic kidney disease or other conditions associated with EPO deficiency.","oneSentence":"GerEPO is an erythropoietin (EPO) analog that stimulates red blood cell production by binding to the erythropoietin receptor on bone marrow progenitor cells.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:47:24.011Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anemia associated with chronic kidney disease"},{"name":"Anemia in patients with cancer receiving chemotherapy"}]},"trialDetails":[{"nctId":"NCT00229099","phase":"PHASE3","title":"Efficacy and Safety Study of GerEPO","status":"COMPLETED","sponsor":"Ministry of Health, Malaysia","startDate":"2005-04","conditions":"Chronic Renal Failure Related Anemia","enrollment":270}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"GerEPO","genericName":"GerEPO","companyName":"Ministry of Health, Malaysia","companyId":"ministry-of-health-malaysia","modality":"Small molecule","firstApprovalDate":"","aiSummary":"GerEPO is an erythropoietin (EPO) analog that stimulates red blood cell production by binding to the erythropoietin receptor on bone marrow progenitor cells. Used for Anemia associated with chronic kidney disease, Anemia in patients with cancer receiving chemotherapy.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}