{"id":"gensci004","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Joint pain"},{"rate":null,"effect":"Carpal tunnel syndrome"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"GenSci004 acts as a growth hormone receptor agonist, binding to and activating growth hormone receptors to stimulate growth, protein synthesis, and metabolic processes. The drug is developed as a therapeutic option for growth hormone deficiency and related growth disorders.","oneSentence":"GenSci004 is a recombinant human growth hormone analog designed to promote growth and metabolic effects.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:13:54.709Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Growth hormone deficiency"},{"name":"Growth disorders in children"}]},"trialDetails":[{"nctId":"NCT06007417","phase":"PHASE3","title":"A Study to Investigate Efficacy and Safety of Weekly PEG-somatropin (GenSci004) in Treatment Naive Children With Growth Hormone Deficiency","status":"UNKNOWN","sponsor":"Changchun GeneScience Pharmaceutical Co., Ltd.","startDate":"2023-12-01","conditions":"GHD","enrollment":162},{"nctId":"NCT06024967","phase":"PHASE3","title":"A Study to Investigate the Safety and Efficacy of Once-weekly PEG-somatropin (GenSci004) in Children With Growth Hormone Deficiency","status":"UNKNOWN","sponsor":"Changchun GeneScience Pharmaceutical Co., Ltd.","startDate":"2023-12-01","conditions":"GHD","enrollment":180}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"GenSci004","genericName":"GenSci004","companyName":"Changchun GeneScience Pharmaceutical Co., Ltd.","companyId":"changchun-genescience-pharmaceutical-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"GenSci004 is a recombinant human growth hormone analog designed to promote growth and metabolic effects. Used for Growth hormone deficiency, Growth disorders in children.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}