{"id":"generic-azelaic-acid-foam","safety":{"commonSideEffects":[{"rate":null,"effect":"Pruritus"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Burning sensation"},{"rate":null,"effect":"Dryness"}]},"_chembl":{"chemblId":"CHEMBL1238","moleculeType":"Small molecule","molecularWeight":"188.22"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Azelaic acid exerts antimicrobial effects against Cutibacterium acnes and has anti-inflammatory properties that reduce erythema and papules. It also normalizes keratinization and reduces the production of inflammatory mediators, making it effective for treating acne and rosacea. The foam formulation enhances skin penetration and patient tolerability.","oneSentence":"Azelaic acid reduces inflammation and bacterial growth in the skin by inhibiting mitochondrial enzymes and reducing reactive oxygen species production.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:13:53.373Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acne vulgaris"},{"name":"Rosacea"}]},"trialDetails":[{"nctId":"NCT03287791","phase":"PHASE3","title":"A Study to Evaluate Safety and Equivalence of Generic Azelaic Acid Foam and Finacea® Foam in Participants With Rosacea","status":"COMPLETED","sponsor":"Actavis Inc.","startDate":"2016-07-19","conditions":"Rosacea","enrollment":924}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Generic Azelaic Acid Foam","genericName":"Generic Azelaic Acid Foam","companyName":"Actavis Inc.","companyId":"actavis-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Azelaic acid reduces inflammation and bacterial growth in the skin by inhibiting mitochondrial enzymes and reducing reactive oxygen species production. Used for Acne vulgaris, Rosacea.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}