{"id":"generex-oral-lyn","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypoglycemia"},{"rate":null,"effect":"Oral/buccal irritation"},{"rate":null,"effect":"Cough"},{"rate":null,"effect":"Throat irritation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Oral-lyn uses Generex's proprietary RapidMist technology to aerosolize insulin for absorption through the oral mucosa (inside the mouth), bypassing the gastrointestinal tract where insulin would be degraded. This allows for non-invasive insulin delivery with rapid onset of action similar to injected insulin.","oneSentence":"Oral-lyn is an oral insulin formulation that delivers insulin through the buccal mucosa to lower blood glucose in diabetes patients.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:13:58.135Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 1 diabetes mellitus"},{"name":"Type 2 diabetes mellitus"}]},"trialDetails":[{"nctId":"NCT00948493","phase":"","title":"Treatment Use of Generex Oral-lyn™ in Patients With Diabetes","status":"NO_LONGER_AVAILABLE","sponsor":"Generex Biotechnology Corp.","startDate":"","conditions":"Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus","enrollment":""},{"nctId":"NCT00668850","phase":"PHASE3","title":"Active Comparator Study of Generex Oral-lyn™ Spray and Injected Human Insulin","status":"UNKNOWN","sponsor":"Generex Biotechnology Corp.","startDate":"2008-04","conditions":"Diabetes Mellitus","enrollment":500}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["buccal Insulin spray"],"phase":"phase_3","status":"active","brandName":"Generex Oral-lyn™","genericName":"Generex Oral-lyn™","companyName":"Generex Biotechnology Corp.","companyId":"generex-biotechnology-corp","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Oral-lyn is an oral insulin formulation that delivers insulin through the buccal mucosa to lower blood glucose in diabetes patients. Used for Type 1 diabetes mellitus, Type 2 diabetes mellitus.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}