{"id":"gelsemium-sempervirens","safety":{"commonSideEffects":[{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Gastrointestinal upset"}]},"_chembl":{"chemblId":"CHEMBL3315352","moleculeType":"Small molecule","molecularWeight":"362.51"},"_dailymed":{"setId":"46f674d1-8a50-4ebe-a0db-d539b75d9129","title":"FLU-COLD (ECHINACEA, ARSENICUM ALBUM, BAPTISIA TINCTORIA, EUPATORIUM PERFOLIATUM, GELSEMIUM SEMPERVIRENS, LYCOPODIUM CLAVATUM, PHOSPHORUS, PYROGENIUM, RHUS TOXICODENDRON) LIQUID [NATURAL WONDERS]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Gelsemium sempervirens contains alkaloids (gelsemine, koumine, and others) that have been studied for potential effects on the central nervous system. In homeopathic practice, it is used for anxiety, tremor, and nervous tension, though the active mechanisms at marketed homeopathic dilutions remain unestablished by conventional pharmacology. The plant extract has shown some activity in animal models related to anxiolytic and muscle relaxant properties.","oneSentence":"Gelsemium sempervirens is a homeopathic preparation derived from the yellow jasmine plant that is traditionally used to modulate anxiety and nervous system function.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:41:31.915Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anxiety and nervous tension (homeopathic indication)"},{"name":"Tremor and muscle tension (traditional use)"}]},"trialDetails":[{"nctId":"NCT00914329","phase":"PHASE3","title":"Gelsemium Sempervirens in Anticipatory Anxiety","status":"COMPLETED","sponsor":"University Hospital, Grenoble","startDate":"2009-06","conditions":"Anxiety","enrollment":180}],"_emaApprovals":[],"_faersSignals":[{"count":6,"reaction":"RASH"},{"count":4,"reaction":"HEPATITIS"},{"count":4,"reaction":"INSOMNIA"},{"count":4,"reaction":"PANCREATITIS"},{"count":3,"reaction":"HEADACHE"},{"count":2,"reaction":"ACNE"},{"count":2,"reaction":"DRUG INTOLERANCE"},{"count":2,"reaction":"DYSPNOEA"},{"count":2,"reaction":"HYPOTENSION"},{"count":2,"reaction":"MALAISE"}],"_approvalHistory":[],"publicationCount":88,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Gelsemium Sempervirens","genericName":"Gelsemium Sempervirens","companyName":"University Hospital, Grenoble","companyId":"university-hospital-grenoble","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Gelsemium sempervirens is a homeopathic preparation derived from the yellow jasmine plant that is traditionally used to modulate anxiety and nervous system function. Used for Anxiety and nervous tension (homeopathic indication), Tremor and muscle tension (traditional use).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}