{"id":"gdc-268-lotion","safety":{"commonSideEffects":[{"rate":"null","effect":"Skin atrophy"},{"rate":"null","effect":"Hypersensitivity"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"GDC 268 Lotion works by inhibiting the production of inflammatory mediators, thereby reducing the symptoms of inflammation and itching. This is achieved through the topical application of a corticosteroid, which is a class of medications that are effective in reducing inflammation and itching. The exact mechanism of action of GDC 268 Lotion is not fully understood, but it is believed to involve the inhibition of phospholipase A2, an enzyme involved in the production of inflammatory mediators.","oneSentence":"GDC 268 Lotion is a topical corticosteroid used to reduce inflammation and itching.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:13:49.116Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Seborrheic dermatitis"}]},"trialDetails":[{"nctId":"NCT03717506","phase":"PHASE3","title":"Bioequivalence Study of Clindamycin Phosphate Topical Lotion, 1% in Subjects With Acne Vulgaris","status":"COMPLETED","sponsor":"Balmoral Medical company","startDate":"2018-10-10","conditions":"Acne Vulgaris","enrollment":1236}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"GDC 268 Lotion","genericName":"GDC 268 Lotion","companyName":"Balmoral Medical company","companyId":"balmoral-medical-company","modality":"Small molecule","firstApprovalDate":"","aiSummary":"GDC 268 Lotion is a topical corticosteroid used to reduce inflammation and itching. Used for Seborrheic dermatitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}