{"id":"gatorade-miralax","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Nausea"},{"rate":"10-20","effect":"Abdominal bloating"},{"rate":"10-20","effect":"Abdominal cramping"},{"rate":"5-15","effect":"Vomiting"},{"rate":"5-10","effect":"Anal irritation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Polyethylene glycol is an osmotic laxative that works by increasing the osmotic pressure in the colon, which pulls water into the bowel and softens stool to facilitate evacuation. This combination is commonly used for bowel preparation prior to colonoscopy or other gastrointestinal procedures. The Gatorade component helps maintain electrolyte balance and hydration during the bowel cleansing process.","oneSentence":"Miralax (polyethylene glycol) draws water into the intestinal lumen to soften stool and promote bowel movements, while Gatorade provides electrolyte and fluid replacement.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:47:02.732Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bowel preparation prior to colonoscopy or other gastrointestinal procedures"},{"name":"Constipation relief"}]},"trialDetails":[{"nctId":"NCT03298945","phase":"PHASE4","title":"Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens","status":"COMPLETED","sponsor":"VA Office of Research and Development","startDate":"2018-12-13","conditions":"Colorectal Cancer","enrollment":2239},{"nctId":"NCT02765256","phase":"PHASE2","title":"Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease","status":"COMPLETED","sponsor":"University of Pennsylvania","startDate":"2016-08","conditions":"Crohn's Disease","enrollment":8},{"nctId":"NCT01695863","phase":"PHASE4","title":"Efficacy and Patient Satisfaction of Miralax and Gatorade Versus Movi Prep","status":"COMPLETED","sponsor":"Rush University Medical Center","startDate":"2012-02","conditions":"Colorectal Cancer","enrollment":150},{"nctId":"NCT03476317","phase":"PHASE2","title":"Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease","status":"COMPLETED","sponsor":"Children's Hospital of Philadelphia","startDate":"2018-07-12","conditions":"Crohn Disease","enrollment":10},{"nctId":"NCT02661750","phase":"","title":"Safety and Efficacy of High Dose Bowel Preparation Solutions for Patients With Difficult To Clean Colons For Colonoscopy","status":"COMPLETED","sponsor":"Gastroenterology Services, Ltd.","startDate":"2016-01","conditions":"Preparation for Colonoscopy","enrollment":79},{"nctId":"NCT01170754","phase":"PHASE4","title":"Miralax (PEG 3350) vs. Golytely as Bowel Preparation for Screening Colonoscopy","status":"COMPLETED","sponsor":"Temple University","startDate":"2010-04","conditions":"Colon Cancer","enrollment":136},{"nctId":"NCT01719653","phase":"PHASE4","title":"A Comparison of 5 Low Volume Bowel Preparations","status":"COMPLETED","sponsor":"Gastroenterology Services, Ltd.","startDate":"2012-10","conditions":"Bowel Preparation for Colonoscopy","enrollment":1079},{"nctId":"NCT01518790","phase":"NA","title":"Short Course, Single-dose PEG 3350 for Colonoscopy Prep in Children","status":"COMPLETED","sponsor":"Walter Reed National Military Medical Center","startDate":"2010-09","conditions":"Colonoscopy","enrollment":50},{"nctId":"NCT01063049","phase":"PHASE4","title":"Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation","status":"COMPLETED","sponsor":"Gastroenterology Services, Ltd.","startDate":"2010-02","conditions":"Preparation for Colonoscopy","enrollment":600},{"nctId":"NCT01299779","phase":"NA","title":"Incidence of Hyponatremia in PEG-SD Compared to PEG-ELS","status":"COMPLETED","sponsor":"Thomas Jefferson University","startDate":"2010-06","conditions":"Hyponatremia","enrollment":460},{"nctId":"NCT00953017","phase":"PHASE4","title":"A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy","status":"COMPLETED","sponsor":"Brooke Army Medical Center","startDate":"2009-07","conditions":"Colonoscopy","enrollment":425},{"nctId":"NCT01028573","phase":"NA","title":"A Study Comparing PEG-3350 (Miralax) and Gatorade With PEG-ELS (Golytely) for Bowel Preparation Prior to Colonoscopy","status":"UNKNOWN","sponsor":"Southern California Institute for Research and Education","startDate":"2009-11","conditions":"Bowel Preparation for Colonoscopy","enrollment":400},{"nctId":"NCT00889655","phase":"PHASE4","title":"A Trial Comparing Bowel Preparation and Patient Tolerability of Miralax Versus Golytely","status":"UNKNOWN","sponsor":"Oregon Health and Science University","startDate":"2009-05","conditions":"Colonoscopy","enrollment":432}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":16,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Gatorade/Miralax","genericName":"Gatorade/Miralax","companyName":"Gastroenterology Services, Ltd.","companyId":"gastroenterology-services-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Miralax (polyethylene glycol) draws water into the intestinal lumen to soften stool and promote bowel movements, while Gatorade provides electrolyte and fluid replacement. Used for Bowel preparation prior to colonoscopy or other gastrointestinal procedures, Constipation relief.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}