{"id":"gastrodia-and-uncaria-drink","brandName":"Gastrodia and Uncaria Drink","genericName":"Gastrodia and Uncaria Drink","companyId":"shanghai-institute-of-hypertension","companyName":"Shanghai Institute of Hypertension","phase":"marketed","status":"active","modality":"Small molecule","aliases":["tianma gouteng drink"],"developmentCodes":[],"firstApprovalDate":null,"firstApprovalCountry":null,"aiSummary":"Gastrodia and Uncaria Drink is a traditional Chinese medicine being evaluated for hypertension. A Phase 4 trial suggests short-term efficacy, but no FDA approval. Limited safety data is available.","enrichmentLevel":3,"visitCount":1,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The formulation combines Gastrodia elata and Uncaria species with other traditional herbs to modulate vascular tone and reduce hypertensive symptoms. The mechanism is attributed to the combined effects of alkaloids and other bioactive compounds that may act on vascular smooth muscle and the central nervous system to lower blood pressure and reduce associated symptoms like dizziness and headache.","oneSentence":"Gastrodia and Uncaria Drink is a traditional Chinese medicine formulation that reduces blood pressure and alleviates hypertension-related symptoms through multiple herbal components.","_ai_confidence":"low"},"administration":{},"safety":{"commonSideEffects":[]},"trials":[],"indications":{"approved":[{"name":"Hypertension"},{"name":"Hypertension-related symptoms (dizziness, headache)"}]},"commercial":null,"patents":[],"timeline":[],"rwe":[],"competitors":[],"ownershipHistory":[],"trialDetails":[{"nctId":"NCT02156024","phase":"PHASE4","title":"The Short-term Efficacy of Gastrodia and Uncaria Drink in Treating Hypertension","status":"UNKNOWN","sponsor":"Shanghai Institute of Hypertension","startDate":"2014-03","conditions":["Masked Hypertension"],"enrollment":400,"completionDate":""}],"genericFilers":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"labelChanges":[],"nice":null,"revenue":null,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}