{"id":"garlic-powder-standardized-to-allicin","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset (nausea, dyspepsia, flatulence)"},{"rate":null,"effect":"Odor (breath and body odor)"},{"rate":null,"effect":"Allergic reactions (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Allicin is a sulfur-containing compound released when garlic is crushed or processed. It acts as a free radical scavenger and modulates inflammatory signaling pathways, potentially reducing oxidative stress and immune dysregulation. Allicin also exhibits direct antimicrobial properties against various pathogens and may influence lipid metabolism and vascular function.","oneSentence":"Allicin, the active compound in garlic powder, exerts antimicrobial, anti-inflammatory, and antioxidant effects through multiple cellular pathways.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:13:45.298Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cardiovascular health and cholesterol management"},{"name":"Immune support and infection prevention"},{"name":"General antioxidant and anti-inflammatory effects"}]},"trialDetails":[{"nctId":"NCT06833125","phase":"PHASE3","title":"The Prophylactic Effect of Garlic Tablets to Prevent Nosocomial Infections in Intensive Care Unit Patients.","status":"ENROLLING_BY_INVITATION","sponsor":"Alexandria University","startDate":"2025-03-01","conditions":"Nosocomial Infection","enrollment":62},{"nctId":"NCT00029250","phase":"PHASE2","title":"Garlic in Hyperlipidemia Caused by HAART","status":"WITHDRAWN","sponsor":"National Center for Complementary and Integrative Health (NCCIH)","startDate":"2001-11","conditions":"HIV Infections, Hypercholesterolemia, Hypertriglyceridemia","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":12,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Garlic powder standardized to allicin","genericName":"Garlic powder standardized to allicin","companyName":"National Center for Complementary and Integrative Health (NCCIH)","companyId":"national-center-for-complementary-and-integrative-health-nccih","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Allicin, the active compound in garlic powder, exerts antimicrobial, anti-inflammatory, and antioxidant effects through multiple cellular pathways. Used for Cardiovascular health and cholesterol management, Immune support and infection prevention, General antioxidant and anti-inflammatory effects.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}