{"id":"ganoderma-lucidum","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Dry mouth"},{"rate":null,"effect":"Allergic reactions (rare)"}]},"_chembl":null,"_dailymed":{"setId":"27b894aa-b3a1-c4a5-e063-6294a90a1662","title":"TRSTAY GANODERMA LUCIDUM CREAM [YIWU XINQIAN E COMMERCE CO LTD]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The fruiting body and spores of Ganoderma lucidum contain bioactive compounds including beta-glucans and ganoderic acids that act as biological response modifiers. These constituents enhance immune surveillance, promote tumor cell death through multiple pathways, and reduce systemic inflammation. The mechanism is multifactorial rather than targeting a single molecular receptor.","oneSentence":"Ganoderma lucidum (reishi mushroom) modulates immune function and promotes apoptosis through polysaccharide and triterpene constituents that enhance natural killer cell activity and reduce inflammatory cytokines.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T03:33:52.192Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cancer adjuvant therapy and immune support"},{"name":"Fatigue and quality of life in cancer patients"}]},"trialDetails":[{"nctId":"NCT06979180","phase":"NA","title":"A Clinical Trial to Investigate the Safety and Efficacy of Papillex® on Abnormal Cervical Cells Caused by HPV.","status":"RECRUITING","sponsor":"Papillex Inc.","startDate":"2026-03","conditions":"CIN - Cervical Intraepithelial Neoplasia, CIN 1, CIN 2","enrollment":60},{"nctId":"NCT07398885","phase":"NA","title":"Assessing the Impact of Herbal Supplement on Fatigue 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Used for Cancer adjuvant therapy and immune support, Fatigue and quality of life in cancer patients.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}