{"id":"ganeden-bc30","safety":{"commonSideEffects":[{"rate":null,"effect":"Mild gastrointestinal symptoms (bloating, gas)"},{"rate":null,"effect":"Transient digestive changes"}]},"_chembl":{"chemblId":"CHEMBL1289157","moleculeType":"Small molecule","molecularWeight":"467.57"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"BC30 is a spore-forming probiotic bacterium that survives stomach acid and colonizes the small intestine, where it produces lactic acid to create an acidic environment that inhibits pathogenic bacteria growth. It also supports the natural gut microbiota balance and may enhance intestinal barrier function and immune response through interaction with gut-associated lymphoid tissue.","oneSentence":"Ganeden BC30 is a probiotic strain of Bacillus coagulans that promotes gastrointestinal health by producing lactic acid and supporting beneficial gut microbiota.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:31:03.264Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Digestive health and gastrointestinal support"},{"name":"Occasional digestive discomfort"}]},"trialDetails":[{"nctId":"NCT01337609","phase":"PHASE4","title":"Study of Probiotic GanedenBC30 for Irritable Bowel Syndrome and Major Depressive Disorder","status":"TERMINATED","sponsor":"Massachusetts General Hospital","startDate":"2011-06","conditions":"Major Depressive Disorder, Irritable Bowel Syndrome","enrollment":5}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Ganeden BC30","genericName":"Ganeden BC30","companyName":"Massachusetts General Hospital","companyId":"massachusetts-general-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ganeden BC30 is a probiotic strain of Bacillus coagulans that promotes gastrointestinal health by producing lactic acid and supporting beneficial gut microbiota. Used for Digestive health and gastrointestinal support, Occasional digestive discomfort.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}