{"id":"gallium-68-tilmanocept","safety":{"commonSideEffects":[{"rate":null,"effect":"Radiation exposure (minimal from diagnostic dose)"},{"rate":null,"effect":"Injection site reactions"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":{"chemblId":"CHEMBL5095039","moleculeType":"Small molecule","molecularWeight":"1029.92"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Tilmanocept is a small-molecule radiopharmaceutical labeled with Gallium-68, a positron-emitting isotope. It targets mannose receptors (CD206) expressed on activated macrophages and other immune cells, allowing PET imaging of inflammatory and infectious lesions. This enables non-invasive visualization and quantification of immune cell infiltration in various disease states.","oneSentence":"Gallium-68-tilmanocept is a radioactive imaging agent that binds to mannose receptors on immune cells to visualize inflammation and infection sites.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:13:39.099Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"PET imaging of infection and inflammation (phase 3 development)"},{"name":"Potential oncology imaging applications for immune cell infiltration assessment"}]},"trialDetails":[{"nctId":"NCT05446324","phase":"PHASE3","title":"Feasibility of Gallium-68-tilmanocept PET/CT for Sentinel Lymph Node Detection in Endometrial Cancer","status":"UNKNOWN","sponsor":"UMC Utrecht","startDate":"2023-02-15","conditions":"Endometrial Cancer","enrollment":10}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["68Ga-tilmanocept"],"phase":"phase_3","status":"active","brandName":"Gallium-68-tilmanocept","genericName":"Gallium-68-tilmanocept","companyName":"UMC Utrecht","companyId":"umc-utrecht","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Gallium-68-tilmanocept is a radioactive imaging agent that binds to mannose receptors on immune cells to visualize inflammation and infection sites. Used for PET imaging of infection and inflammation (phase 3 development), Potential oncology imaging applications for immune cell infiltration assessment.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}