{"id":"galactose","rwe":[],"tags":[{"label":"galactose","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"V04CE01","category":"atc"},{"label":"Active","category":"status"}],"phase":"discontinued","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"_fixedAt":"2026-03-30T16:59:11.316573","allNames":"galactopyranose","offLabel":[],"synonyms":["galactose","galactopyranose","alpha-D-Galactopyranose","microparticles of galactose"],"timeline":[],"aiSummary":"Galactose is a naturally occurring sugar molecule that serves as a galactose, a small molecule modality. Its mechanism of action is not well established, and it is not FDA approved for any indications. As a naturally occurring compound, galactose is not patented and is likely available from generic manufacturers. However, its commercial status and safety profile are not well documented. Further research is needed to understand its potential therapeutic applications and safety considerations.","approvals":[],"brandName":"Galactopyranose","ecosystem":[],"mechanism":{"target":"Jacalin","modality":"Small Molecule","drugClass":"galactose","explanation":"Imagine your cells are like a factory, and galactose is a special messenger that helps regulate the flow of materials and energy within the factory. By interacting with receptors and enzymes, galactose can influence how the factory operates, potentially leading to changes in cellular behavior and function. This can have various effects on the body, depending on the specific pathways involved.","oneSentence":"Galactose works by interacting with cellular receptors and enzymes to influence various biological pathways.","technicalDetail":"Galactose interacts with cell surface receptors, such as lectins, and intracellular enzymes, such as glycosidases, to modulate glycosylation patterns and influence signaling pathways involved in cell growth, differentiation, and survival."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1271","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=GALACTOSE","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=GALACTOSE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:57:24.054960","biosimilars":[],"competitors":[],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"galactose","indications":{"approved":[],"offLabel":[],"pipeline":[]},"_fixedFields":["pubmed(40031)"],"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT05402332","phase":"PHASE2","title":"Evaluating the Efficacy and Safety of D-galactose in PGM1-CDG (AVTX-801)","status":"NOT_YET_RECRUITING","sponsor":"Eva Morava-Kozicz","startDate":"2026-10-01","conditions":["PGM1-CDG - 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In practice"},{"date":"2026 Mar 27","pmid":"41905596","title":"Absence of glomerular IgA1 deposition despite overexpression of galactose-deficient IgA1 in the B cell c1galt1 knockout mouse.","journal":"Kidney international"},{"date":"2026 Mar 26","pmid":"41903633","title":"Structural basis for galactose side-chain recognition in isoprimeverose-producing oligoxyloglucan hydrolase from Phaeoacremonium minimum.","journal":"International journal of biological macromolecules"},{"date":"2026 Mar 12","pmid":"41901393","title":"Multi-Omics Analysis Reveals Crucial Mechanisms by Which Shading Intensity Regulates Sugar Metabolism in Asparagus Stems.","journal":"Plants (Basel, Switzerland)"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"discontinued","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}