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The intravenous formulation provides rapid onset of action suitable for acute decompensated heart failure and other conditions requiring urgent diuresis.","oneSentence":"Furosemide inhibits sodium and chloride reabsorption in the thick ascending limb of the loop of Henle, promoting diuresis and reducing fluid overload.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:46:43.010Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute decompensated heart failure with fluid overload"},{"name":"Pulmonary edema"},{"name":"Edema associated with renal disease or hepatic cirrhosis"},{"name":"Hypertension"}]},"trialDetails":[{"nctId":"NCT07464249","phase":"NA","title":"Comparison of the Effectiveness of Different Diuretic Therapies in the Management of Acute Heart Failure","status":"COMPLETED","sponsor":"Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey","startDate":"2024-04-03","conditions":"Acute Decompensated Heart Failure 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