{"id":"furazidin","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"J01XE03","category":"atc"},{"label":"Active","category":"status"},{"label":"Urinary tract infectious disease","category":"indication"},{"label":"Anti-Infective Agents","category":"pharmacology"},{"label":"Anti-Infective Agents, Urinary","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"furagin","offLabel":[],"synonyms":["furazidin","furagin","furazidine","furamag","furasol","furazidin potassium","solafur"],"timeline":[],"approvals":[],"brandName":"Furagin","ecosystem":[{"indication":"Urinary tract infectious disease","otherDrugs":[{"name":"Polymyxin B","slug":"polymyxin-b","company":"Monarch Pharms"},{"name":"acetohydroxamic acid","slug":"acetohydroxamic-acid","company":"Mission Pharma"},{"name":"alatrofloxacin","slug":"alatrofloxacin","company":"Pfizer"},{"name":"amoxicillin","slug":"amoxicillin","company":"Apothecon"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","explanation":"Think of it like a brake on a car - Furagin puts the brakes on bacterial growth by stopping the enzyme that helps bacteria make copies of themselves. This prevents the infection from getting worse and allows the body's immune system to fight off the infection. By stopping bacterial growth, Furagin helps to clear up the infection and prevent further complications.","oneSentence":"Furagin works by inhibiting bacterial growth and replication, specifically targeting the bacterial enzyme responsible for DNA synthesis.","technicalDetail":"Furagin is believed to exert its antibacterial effects through the inhibition of dihydrofolate reductase, an enzyme essential for the synthesis of tetrahydrofolate, a precursor to thymidylate and purines, which are critical for DNA synthesis and repair."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4869","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=furazidin","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:37:44.727091","biosimilars":[],"competitors":[{"drugName":"nitrofurantoin","drugSlug":"nitrofurantoin","fdaApproval":"1953-02-06","genericCount":15,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"furazidin","indications":{"approved":[{"name":"Urinary tract infectious disease","source":"DrugCentral","snomedId":68566005,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"nitrofurantoin","brandName":"nitrofurantoin","genericName":"nitrofurantoin","approvalYear":"1953","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"K2R4N34Y9I","CHEBI":"CHEBI:131714","UMLSCUI":"C0016848","ChEMBL_ID":"CHEMBL3707254","KEGG_DRUG":"D07998","DRUGBANK_ID":"DB13475","PUBCHEM_CID":"6870646","IUPHAR_LIGAND_ID":"12367","MESH_DESCRIPTOR_UI":"D005661","MESH_SUPPLEMENTAL_RECORD_UI":"C032005"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":25,"therapeuticAreas":["Infectious Disease"],"atcClassification":{"source":"DrugCentral","atcCode":"J01XE03","allCodes":["J01XE03"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Furagin (furazidin) is a small molecule modality developed for the treatment of urinary tract infectious diseases. Although its exact target and drug class are unknown, it has been approved for use in treating urinary tract infections. The commercial status of Furagin is unclear, with no information available on its patent status or generic manufacturers. Further research is needed to fully understand its pharmacokinetic properties and potential safety considerations. As a result, its use should be approached with caution and under the guidance of a qualified healthcare professional.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}