{"id":"furaltadone","rwe":[{"pmid":"41628594","year":"2026","title":"A Self-Catenated Metal-Organic Framework with Asymmetric Linkers and Its Adsorption of Furaltadone Antibiotic.","finding":"","journal":"Inorganic chemistry","studyType":"Clinical Study"},{"pmid":"41146649","year":"2025","title":"Poultry-associated nitrofurantoin-resistant and pre-resistant Escherichia coli clones are found in multiple countries and one-health compartments.","finding":"","journal":"One health (Amsterdam, Netherlands)","studyType":"Clinical Study"},{"pmid":"41076910","year":"2025","title":"Design of laser-induced graphene-based electrochemical sensing platforms for residue analysis of nitrofurans in aquaculture environment.","finding":"","journal":"Journal of hazardous materials","studyType":"Clinical Study"},{"pmid":"40748524","year":"2025","title":"A conjugated pyridine diimine fluorene-based polymer for the detection of furaltadone.","finding":"","journal":"Analytical sciences : the international journal of the Japan Society for Analytical Chemistry","studyType":"Clinical Study"},{"pmid":"39350687","year":"2024","title":"An imidazole functionalized aqua-stable metal-organic framework for selective fluorogenic detection of herbicide DNOC and antibacterial agent furaltadone in various biological and environmental specimens.","finding":"","journal":"Dalton transactions (Cambridge, England : 2003)","studyType":"Clinical Study"}],"tags":[{"label":"furaltadone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Mitogen-activated protein kinase 9","category":"target"},{"label":"MAPK9","category":"gene"},{"label":"Active","category":"status"},{"label":"Anti-Infective Agents","category":"pharmacology"},{"label":"Anti-Infective Agents, Urinary","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"furazolin","offLabel":[],"synonyms":["furaltadone","furmethanol","furmethonol","furmetonol","medifuran","furaltadon","furantoina","furazolin","furazoline","nitraldone","nitrofurmethone","nitrofurmeton","furaltadone hydrochloride","furaltadone HCl"],"timeline":[],"approvals":[],"brandName":"Furazolin","ecosystem":[],"mechanism":{"target":"Mitogen-activated protein kinase 9","targets":[{"gene":"MAPK9","source":"DrugCentral","target":"Mitogen-activated protein kinase 9","protein":"Mitogen-activated protein kinase 9"}],"modality":"Small Molecule","drugClass":"furaltadone","explanation":"Think of cell signaling like a messenger system. MAPK9 is a key messenger that helps cells respond to stress and inflammation. By blocking MAPK9, Furazolin may help reduce inflammation and other symptoms associated with certain diseases.","oneSentence":"Furazolin works by inhibiting the activity of Mitogen-activated protein kinase 9 (MAPK9), a protein involved in cell signaling pathways.","technicalDetail":"Furazolin exerts its effects by binding to the ATP-binding site of MAPK9, thereby inhibiting its kinase activity and downstream signaling pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1256","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=FURALTADONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:37:40.612824","biosimilars":[],"competitors":[{"drugName":"afatinib","drugSlug":"afatinib","fdaApproval":"2013-07-12","patentExpiry":"Oct 10, 2029","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"encorafenib","drugSlug":"encorafenib","fdaApproval":"2018-06-27","patentExpiry":"Nov 21, 2032","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"erlotinib","drugSlug":"erlotinib","fdaApproval":"2004-11-18","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"fedratinib","drugSlug":"fedratinib","fdaApproval":"2019-08-16","patentExpiry":"Sep 24, 2039","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"fostamatinib","drugSlug":"fostamatinib","fdaApproval":"2018-04-17","patentExpiry":"Sep 4, 2031","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"gefitinib","drugSlug":"gefitinib","fdaApproval":"2003-05-05","genericCount":5,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"gilteritinib","drugSlug":"gilteritinib","fdaApproval":"2018-11-28","patentExpiry":"Nov 28, 2032","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"imatinib","drugSlug":"imatinib","fdaApproval":"2001-05-10","patentExpiry":"Apr 27, 2040","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"midostaurin","drugSlug":"midostaurin","fdaApproval":"2017-04-28","patentExpiry":"Oct 9, 2028","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"nilotinib","drugSlug":"nilotinib","fdaApproval":"2007-10-29","patentStatus":"Unknown","relationship":"same-target"}],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"furaltadone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"afatinib","brandName":"afatinib","genericName":"afatinib","approvalYear":"2013","relationship":"same-target"},{"drugId":"encorafenib","brandName":"encorafenib","genericName":"encorafenib","approvalYear":"2018","relationship":"same-target"},{"drugId":"erlotinib","brandName":"erlotinib","genericName":"erlotinib","approvalYear":"2004","relationship":"same-target"},{"drugId":"fedratinib","brandName":"fedratinib","genericName":"fedratinib","approvalYear":"2019","relationship":"same-target"},{"drugId":"fostamatinib","brandName":"fostamatinib","genericName":"fostamatinib","approvalYear":"2018","relationship":"same-target"},{"drugId":"gefitinib","brandName":"gefitinib","genericName":"gefitinib","approvalYear":"2003","relationship":"same-target"},{"drugId":"gilteritinib","brandName":"gilteritinib","genericName":"gilteritinib","approvalYear":"2018","relationship":"same-target"},{"drugId":"imatinib","brandName":"imatinib","genericName":"imatinib","approvalYear":"2001","relationship":"same-target"},{"drugId":"midostaurin","brandName":"midostaurin","genericName":"midostaurin","approvalYear":"2017","relationship":"same-target"},{"drugId":"nilotinib","brandName":"nilotinib","genericName":"nilotinib","approvalYear":"2007","relationship":"same-target"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"NDDF":"002856","UNII":"5X4V82ZN30","CHEBI":"CHEBI:74803","INN_ID":"811","UMLSCUI":"C0060849","ChEMBL_ID":"CHEMBL1189513","KEGG_DRUG":"D02510","DRUGBANK_ID":"DB16567","PUBCHEM_CID":"9553856","SECONDARY_CAS_RN":"3759-92-0","MESH_SUPPLEMENTAL_RECORD_UI":"C007795"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":181,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 Feb 16","pmid":"41628594","title":"A Self-Catenated Metal-Organic Framework with Asymmetric Linkers and Its Adsorption of Furaltadone Antibiotic.","journal":"Inorganic chemistry"},{"date":"2025 Dec","pmid":"41146649","title":"Poultry-associated nitrofurantoin-resistant and pre-resistant Escherichia coli clones are found in multiple countries and one-health compartments.","journal":"One health (Amsterdam, Netherlands)"},{"date":"2025 Nov 5","pmid":"41076910","title":"Design of laser-induced graphene-based electrochemical sensing platforms for residue analysis of nitrofurans in aquaculture environment.","journal":"Journal of hazardous materials"},{"date":"2025 Oct","pmid":"40748524","title":"A conjugated pyridine diimine fluorene-based polymer for the detection of furaltadone.","journal":"Analytical sciences : the international journal of the Japan Society for Analytical Chemistry"},{"date":"2024 Oct 22","pmid":"39350687","title":"An imidazole functionalized aqua-stable metal-organic framework for selective fluorogenic detection of herbicide DNOC and antibacterial agent furaltadone in various biological and environmental specimens.","journal":"Dalton transactions (Cambridge, England : 2003)"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Furazolin, also known as Furaltadone, is a small molecule drug that targets Mitogen-activated protein kinase 9 (MAPK9). It belongs to the furaltadone class and its mechanism of action is not well-documented. There is limited information available on its commercial status, approved indications, and pharmacokinetic properties. Further research is needed to understand its potential therapeutic applications and safety profile. As a result, it is not clear if Furazolin is patented or available as a generic medication.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}