{"id":"fudosteine","rwe":[],"tags":[{"label":"fudosteine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{"safetySignals":[{"llr":57.501,"date":"","count":32,"signal":"Pneumonia","source":"DrugCentral FAERS","actionTaken":"Reported 32 times (LLR=58)"}],"commonSideEffects":[{"effect":"Pneumonia","drugRate":"LLR 58","severity":"common"}]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"cleanal","offLabel":[],"synonyms":["fudosteine","cleanal"],"timeline":[],"approvals":[],"brandName":"Cleanal","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"fudosteine","explanation":"Think of acetylcholine like a messenger in your body that helps your muscles relax and your airways open. When acetylcholinesterase breaks it down, the message is lost. Cleanal blocks this enzyme, allowing acetylcholine to stay active longer and help your body relax and open up your airways.","oneSentence":"Cleanal works by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine.","technicalDetail":"Fudosteine is a reversible cholinesterase inhibitor that selectively targets acetylcholinesterase, thereby increasing the concentration and duration of action of acetylcholine in the synaptic cleft."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1254","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=FUDOSTEINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:37:33.776517","biosimilars":[],"competitors":[],"genericName":"fudosteine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"UR9VPI71PT","CHEBI":"CHEBI:31637","INN_ID":"7613","UMLSCUI":"C0756016","ChEMBL_ID":"CHEMBL1555183","KEGG_DRUG":"D01845","PUBCHEM_CID":"134669","MESH_SUPPLEMENTAL_RECORD_UI":"C113797"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":30,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cleanal (FUDOSTEINE) is a small molecule drug in the fudosteine class, but specific details about its target, indications, and commercial status are unknown. As a fudosteine, it is likely involved in the treatment of respiratory conditions, but further information is needed to confirm its use. The mechanism of action and pharmacokinetic properties of Cleanal are also unclear. Further research is necessary to determine its safety profile and potential side effects. As a result, Cleanal is not yet a well-established treatment option.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":true,"trials":false,"score":2}}