{"id":"freezed-dried-plasma","safety":{"commonSideEffects":[{"rate":null,"effect":"Thromboembolic events"},{"rate":null,"effect":"Transfusion-related acute lung injury (TRALI)"},{"rate":null,"effect":"Allergic reactions"},{"rate":null,"effect":"Infection transmission risk"}]},"_chembl":{"chemblId":"CHEMBL2108815","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Freeze-dried plasma is a lyophilized form of human plasma that contains all vitamin K-dependent coagulation factors (II, V, VII, X), fibrinogen, and other plasma proteins. Upon reconstitution with sterile water, it restores hemostatic capacity in patients with factor deficiencies, massive transfusion, or coagulopathy. It serves as an alternative to fresh frozen plasma with improved shelf-life and storage stability.","oneSentence":"Freeze-dried plasma reconstitutes fresh frozen plasma to restore coagulation factors and hemostatic function in patients with bleeding or coagulopathy.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:13:24.261Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute bleeding due to coagulation factor deficiency"},{"name":"Massive transfusion protocol support"},{"name":"Reversal of anticoagulation in emergency settings"}]},"trialDetails":[{"nctId":"NCT02750150","phase":"PHASE3","title":"Freeze-dried Plasma in the Initial Management of Coagulopathy in Trauma Patients","status":"COMPLETED","sponsor":"University Hospital, Lille","startDate":"2013-07-09","conditions":"Trauma, Coagulopathy","enrollment":42}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Freezed-dried plasma","genericName":"Freezed-dried plasma","companyName":"University Hospital, Lille","companyId":"university-hospital-lille","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Freeze-dried plasma reconstitutes fresh frozen plasma to restore coagulation factors and hemostatic function in patients with bleeding or coagulopathy. Used for Acute bleeding due to coagulation factor deficiency, Massive transfusion protocol support, Reversal of anticoagulation in emergency settings.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}