{"id":"follitrope-pfs","safety":{"commonSideEffects":[{"rate":null,"effect":"Ovarian hyperstimulation syndrome (OHSS)"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Injection site reactions"},{"rate":null,"effect":"Abdominal pain/bloating"},{"rate":null,"effect":"Nausea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Follitrope PFS binds to FSH receptors on granulosa cells of ovarian follicles, promoting follicular development and estrogen production. This hormone is used in assisted reproductive technology (ART) protocols to induce controlled ovarian hyperstimulation, enabling the retrieval of multiple mature oocytes for in vitro fertilization or other fertility procedures.","oneSentence":"Follitrope PFS is a recombinant follicle-stimulating hormone (FSH) that stimulates the growth and maturation of ovarian follicles in women undergoing fertility treatment.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:13:20.104Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Infertility in women undergoing assisted reproductive technology (ART)"},{"name":"Controlled ovarian hyperstimulation for oocyte retrieval"}]},"trialDetails":[{"nctId":"NCT04227171","phase":"","title":"Observational Study to Develop Dosing Chart","status":"COMPLETED","sponsor":"LG Chem","startDate":"2018-08-03","conditions":"Infertile Women Undergoing IVF or ICSI","enrollment":534},{"nctId":"NCT03506243","phase":"PHASE3","title":"Randomized Controlled Study of Comparing Follitrope Versus Gonal-f in Chinese Infertility Women.","status":"COMPLETED","sponsor":"Hangzhou YuYuan Bioscience Technology Co., Ltd.","startDate":"2015-04","conditions":"Infertility, Female","enrollment":451}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Follitrope PFS","genericName":"Follitrope PFS","companyName":"Hangzhou YuYuan Bioscience Technology Co., Ltd.","companyId":"hangzhou-yuyuan-bioscience-technology-co-ltd","modality":"Biologic","firstApprovalDate":"","aiSummary":"Follitrope PFS is a recombinant follicle-stimulating hormone (FSH) that stimulates the growth and maturation of ovarian follicles in women undergoing fertility treatment. Used for Infertility in women undergoing assisted reproductive technology (ART), Controlled ovarian hyperstimulation for oocyte retrieval.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}