{"id":"fluoroethylcholine-18f","rwe":[{"pmid":"41177835","year":"2026","title":"Diagnostic performance of quantitative measures from [(18)F]FDG PET/CT, [(18)F]FEC PET/CT, and DW-MRI in the detection of lymph node metastases in endometrial and cervical cancer: data from the MAPPING study.","finding":"","journal":"European journal of nuclear medicine and molecular imaging","studyType":"Clinical Study"},{"pmid":"39900666","year":"2025","title":"[Molecular breast imaging : Positron emission tomography/magnetic resonance imaging and targeted tracers].","finding":"","journal":"Radiologie (Heidelberg, Germany)","studyType":"Clinical Study"},{"pmid":"39759560","year":"2024","title":"Tracing prostate cancer - the evolution of PET-CT applications.","finding":"","journal":"Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology","studyType":"Clinical Study"},{"pmid":"37221356","year":"2023","title":"Prospective validation of 18F-Fluoroethylcholine as a tracer in PET/MRI for the evaluation of breast lesions and prediction of lymph node status.","finding":"","journal":"La Radiologia medica","studyType":"Clinical Study"},{"pmid":"33208625","year":"2021","title":"Quantitative Features From CHO PET Distinguish the WHO Grades of Primary Diffuse Glioma.","finding":"","journal":"Clinical nuclear medicine","studyType":"Clinical Study"}],"tags":[{"label":"fluoroethylcholine (18F)","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"V09IX08","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["fluoroethylcholine (18F)"],"offLabel":[],"synonyms":["fluoroethylcholine (18F)"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"fluoroethylcholine (18F)","explanation":"Imagine your body as a city with many different buildings. Fluoroethylcholine (18F) is a special key that finds and attaches to a specific building, allowing doctors to see that building on a scan. This helps doctors diagnose and understand diseases that affect that building.","oneSentence":"Fluoroethylcholine (18F) works by binding to a specific target in the body, allowing for diagnostic imaging.","technicalDetail":"Fluoroethylcholine (18F) is a positron-emitting radiopharmaceutical that accumulates in cells with high choline uptake, such as cancer cells, allowing for PET imaging."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4551","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=fluoroethylcholine%20%2818F%29","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=fluoroethylcholine (18F)","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:34:16.639671","biosimilars":[],"competitors":[{"drugName":"iobenguane (123I)","drugSlug":"iobenguane-(123i)","fdaApproval":"2008-09-19","relationship":"same-class"},{"drugName":"iobenguane (131I)","drugSlug":"iobenguane-(131i)","fdaApproval":"1994-03-25","relationship":"same-class"},{"drugName":"fludeoxyglucose (18F)","drugSlug":"fludeoxyglucose-(18f)","fdaApproval":"1994-08-19","relationship":"same-class"},{"drugName":"fluorodopa (18F)","drugSlug":"fluorodopa-(18f)","fdaApproval":"2019-10-10","relationship":"same-class"},{"drugName":"sodium fluoride F-18","drugSlug":"sodium-fluoride-f-18","fdaApproval":"1972-02-24","genericCount":23,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"gallium (68Ga) edotreotide","drugSlug":"gallium-(68ga)-edotreotide","fdaApproval":"2019-08-21","relationship":"same-class"},{"drugName":"fluoroestradiol F 18","drugSlug":"fluoroestradiol-f-18","fdaApproval":"2020-05-20","relationship":"same-class"},{"drugName":"fluciclovine (18F)","drugSlug":"fluciclovine-(18f)","fdaApproval":"2016-05-27","relationship":"same-class"},{"drugName":"methionine","drugSlug":"methionine","fdaApproval":"","relationship":"same-class"},{"drugName":"gallium (68Ga) gozetotide","drugSlug":"gallium-(68ga)-gozetotide","fdaApproval":"2020-12-01","relationship":"same-class"},{"drugName":"copper dotatate Cu-64","drugSlug":"copper-dotatate-cu-64","fdaApproval":"2020-09-03","relationship":"same-class"}],"genericName":"fluoroethylcholine (18f)","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"iobenguane-(123i)","brandName":"iobenguane (123I)","genericName":"iobenguane (123I)","approvalYear":"2008","relationship":"same-class"},{"drugId":"iobenguane-(131i)","brandName":"iobenguane (131I)","genericName":"iobenguane (131I)","approvalYear":"1994","relationship":"same-class"},{"drugId":"fludeoxyglucose-(18f)","brandName":"fludeoxyglucose (18F)","genericName":"fludeoxyglucose (18F)","approvalYear":"1994","relationship":"same-class"},{"drugId":"fluorodopa-(18f)","brandName":"fluorodopa (18F)","genericName":"fluorodopa (18F)","approvalYear":"2019","relationship":"same-class"},{"drugId":"sodium-fluoride-f-18","brandName":"sodium fluoride F-18","genericName":"sodium fluoride F-18","approvalYear":"1972","relationship":"same-class"},{"drugId":"gallium-(68ga)-edotreotide","brandName":"gallium (68Ga) edotreotide","genericName":"gallium (68Ga) edotreotide","approvalYear":"2019","relationship":"same-class"},{"drugId":"fluoroestradiol-f-18","brandName":"fluoroestradiol F 18","genericName":"fluoroestradiol F 18","approvalYear":"2020","relationship":"same-class"},{"drugId":"fluciclovine-(18f)","brandName":"fluciclovine (18F)","genericName":"fluciclovine (18F)","approvalYear":"2016","relationship":"same-class"},{"drugId":"methionine","brandName":"methionine","genericName":"methionine","approvalYear":"","relationship":"same-class"},{"drugId":"gallium-(68ga)-gozetotide","brandName":"gallium (68Ga) gozetotide","genericName":"gallium (68Ga) gozetotide","approvalYear":"2020","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT00943462","phase":"","title":"Study of 18F-FEC for Positron Emission Tomography-Computed Tomography (PET-CT) Imaging of GBM","status":"WITHDRAWN","sponsor":"Centre hospitalier de l'Université de Montréal (CHUM)","startDate":"2009-06","conditions":["Astrocytoma, Grade IV","Giant Cell Glioblastoma","Glioblastoma Multiforme"],"enrollment":0,"completionDate":"2011-06"},{"nctId":"NCT02238769","phase":"","title":"18F-FluoroethylCholine Positron Emission Tomography: a Promising Diagnostic Tool for Hepatocellular Carcinoma","status":"UNKNOWN","sponsor":"Peking Union Medical College Hospital","startDate":"2014-07","conditions":["Hepatocellular Carcinoma"],"enrollment":80,"completionDate":"2017-10"},{"nctId":"NCT00520546","phase":"PHASE3","title":"Clinical Value of FEC-PET Combined With Endorectal MRI for Pre-therapeutic Staging of Prostate Cancer","status":"COMPLETED","sponsor":"Dr. Markus Hartenbach","startDate":"2007-12","conditions":["Prostate Cancer"],"enrollment":44,"completionDate":"2011-06"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"QQW28RS4Z8","UMLSCUI":"C2348690","ChEMBL_ID":"CHEMBL3707264","PUBCHEM_CID":"10103319","SECONDARY_CAS_RN":"407582-17-6"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":44,"therapeuticAreas":["Oncology"],"atcClassification":{"source":"DrugCentral","atcCode":"V09IX08","allCodes":["V09IX08"]},"biosimilarFilings":[],"recentPublications":[{"date":"2026 Mar","pmid":"41177835","title":"Diagnostic performance of quantitative measures from [(18)F]FDG PET/CT, [(18)F]FEC PET/CT, and DW-MRI in the detection of lymph node metastases in endometrial and cervical cancer: data from the MAPPING study.","journal":"European journal of nuclear medicine and molecular imaging"},{"date":"2025 Mar","pmid":"39900666","title":"[Molecular breast imaging : Positron emission tomography/magnetic resonance imaging and targeted tracers].","journal":"Radiologie (Heidelberg, Germany)"},{"date":"2024","pmid":"39759560","title":"Tracing prostate cancer - the evolution of PET-CT applications.","journal":"Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology"},{"date":"2023 Jun","pmid":"37221356","title":"Prospective validation of 18F-Fluoroethylcholine as a tracer in PET/MRI for the evaluation of breast lesions and prediction of lymph node status.","journal":"La Radiologia medica"},{"date":"2021 Feb 1","pmid":"33208625","title":"Quantitative Features From CHO PET Distinguish the WHO Grades of Primary Diffuse Glioma.","journal":"Clinical nuclear medicine"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"fluoroethylcholine (18F)","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Fluoroethylcholine (18F) is a small molecule radiopharmaceutical in the fluoroethylcholine class. Its exact target is unknown, but it is used in nuclear medicine for diagnostic imaging. The commercial status of fluoroethylcholine (18F) is unclear, and it may be patented or have generic manufacturers. There is limited information available on its half-life, bioavailability, and approved indications. Further research is needed to fully understand its properties and uses.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}