{"id":"flumedroxone","rwe":[{"pmid":"716957","year":"1978","title":"Solubilization of spironolactone and flumedroxone acetate.","finding":"","journal":"Acta pharmaceutica Suecica","studyType":"Clinical Study"},{"pmid":"5817457","year":"1969","title":"Prophylactic treatment of migraine with flumedroxone.","finding":"","journal":"Acta neurologica Scandinavica","studyType":"Clinical Study"},{"pmid":"4877801","year":"1968","title":"Double-blind controlled trial of a micronized preparation of flumedroxone (Demigran) in prophylaxis of migraine.","finding":"","journal":"British medical journal","studyType":"Clinical Study"}],"tags":[{"label":"flumedroxone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N02CB01","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"praemenstron","offLabel":[],"synonyms":["flumedroxone","praemenstron"],"timeline":[],"approvals":[],"brandName":"Praemenstron","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"flumedroxone","explanation":"Imagine your body's cells have locks on them, and the key to unlocking these locks is a specific shape that fits perfectly. Praemenstron is like a key that tries to fit into these locks, but we don't know which lock it's meant to open or how it will affect the body's overall function.","oneSentence":"Praemenstron is thought to work by interacting with a specific biological target, although the exact nature of this interaction is not yet fully understood.","technicalDetail":"Praemenstron is a small molecule that binds to a specific protein or receptor, potentially modulating its activity and leading to downstream effects on cellular function."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4547","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=FLUMEDROXONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:30:43.297919","biosimilars":[],"competitors":[],"genericName":"flumedroxone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"K80185F39X","CHEBI":"CHEBI:135987","INN_ID":"2035","UMLSCUI":"C0060492","ChEMBL_ID":"CHEMBL2104932","KEGG_DRUG":"D07296","DRUGBANK_ID":"DB13610","PUBCHEM_CID":"20055352","MESH_SUPPLEMENTAL_RECORD_UI":"C007732"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"N02CB01","allCodes":["N02CB01"]},"biosimilarFilings":[],"recentPublications":[{"date":"1978","pmid":"716957","title":"Solubilization of spironolactone and flumedroxone acetate.","journal":"Acta pharmaceutica Suecica"},{"date":"1969","pmid":"5817457","title":"Prophylactic treatment of migraine with flumedroxone.","journal":"Acta neurologica Scandinavica"},{"date":"1968 Aug 31","pmid":"4877801","title":"Double-blind controlled trial of a micronized preparation of flumedroxone (Demigran) in prophylaxis of migraine.","journal":"British medical journal"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Praemenstron, also known as flumedroxone, is a small molecule drug of the flumedroxone class. Its exact target and mechanism of action are unknown, and it has not been approved by the FDA for any indications. As a result, there is limited information available on its commercial status, pharmacokinetics, or safety profile. Further research is needed to fully understand the properties and potential uses of praemenstron. It is not currently available as a generic medication.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}