{"id":"fluidotherapy-with-ringer-lactate","safety":{"commonSideEffects":[{"rate":null,"effect":"Hyperkalemia (in renal impairment)"},{"rate":null,"effect":"Fluid overload / pulmonary edema"},{"rate":null,"effect":"Hyperchloremic acidosis (with large volumes)"},{"rate":null,"effect":"Phlebitis at infusion site"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Ringer-lactate is a crystalloid solution containing sodium, potassium, calcium, chloride, and lactate in physiologic concentrations. When administered intravenously, it replaces lost fluids and electrolytes, restores circulating blood volume, and maintains cellular function. The lactate component is metabolized by the liver to bicarbonate, providing mild alkalinizing effects.","oneSentence":"Fluidotherapy with Ringer-lactate is an intravenous fluid replacement therapy that restores intravascular volume and electrolyte balance in dehydrated or hypovolemic patients.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:46:38.736Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypovolemia and dehydration management"},{"name":"Perioperative fluid replacement"},{"name":"Burn injury fluid resuscitation"},{"name":"Hemorrhagic shock management"}]},"trialDetails":[{"nctId":"NCT00860704","phase":"PHASE4","title":"Goal Directed Fluid Therapy","status":"COMPLETED","sponsor":"Medical University of Vienna","startDate":"2007-11","conditions":"Goal Directed Fluid Therapy","enrollment":90}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"fluidotherapy with ringer-lactate","genericName":"fluidotherapy with ringer-lactate","companyName":"Medical University of Vienna","companyId":"medical-university-of-vienna","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Fluidotherapy with Ringer-lactate is an intravenous fluid replacement therapy that restores intravascular volume and electrolyte balance in dehydrated or hypovolemic patients. Used for Hypovolemia and dehydration management, Perioperative fluid replacement, Burn injury fluid resuscitation.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}