{"id":"fluad-and-ppv23-on-the-different-arms","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain/erythema"},{"rate":null,"effect":"Myalgia"},{"rate":null,"effect":"Fatigue"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Low-grade fever"}]},"_chembl":{"chemblId":"CHEMBL3544516","moleculeType":"Small molecule","molecularWeight":"375.87"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Fluad is an inactivated influenza vaccine adjuvanted with MF59, designed to enhance immune response to seasonal influenza. PPV23 (pneumococcal polysaccharide vaccine) provides protection against 23 serotypes of Streptococcus pneumoniae. This study compares these vaccines when given on different arms rather than co-administered, likely to evaluate potential immunological interference or optimal spacing.","oneSentence":"This is a comparative study evaluating two different vaccines (Fluad and PPV23) administered on separate study arms to assess immunogenicity and safety in a specific population.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:39:42.347Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Seasonal influenza prevention (Fluad)"},{"name":"Pneumococcal disease prevention (PPV23)"}]},"trialDetails":[{"nctId":"NCT02225327","phase":"PHASE4","title":"MF59-adjuvanted Influenza Vaccine and 23-valent Pneumococcal Polysaccharide Vaccine","status":"COMPLETED","sponsor":"Korea University Guro Hospital","startDate":"2013-10","conditions":"Influenza, Human, Pneumococcal Infections","enrollment":224}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Fluad and PPV23 on the different arms","genericName":"Fluad and PPV23 on the different arms","companyName":"Korea University Guro Hospital","companyId":"korea-university-guro-hospital","modality":"Biologic","firstApprovalDate":"","aiSummary":"This is a comparative study evaluating two different vaccines (Fluad and PPV23) administered on separate study arms to assess immunogenicity and safety in a specific population. Used for Seasonal influenza prevention (Fluad), Pneumococcal disease prevention (PPV23).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}