{"id":"florantyrone","rwe":[{"pmid":"2932325","year":"1985","title":"Action of drugs and chemical agents on rat liver regeneration.","finding":"","journal":"Drug and chemical toxicology","studyType":"Clinical Study"},{"pmid":"4434947","year":"1974","title":"Proceedings: The effect of florantyrone (Zanchol) on the composition of T-tube bile.","finding":"","journal":"Gut","studyType":"Clinical Study"},{"pmid":"5846616","year":"1965","title":"[Formation of biliverdin by the action of florantyrone].","finding":"","journal":"Medicina","studyType":"Clinical Study"},{"pmid":"14483923","year":"1961","title":"A study of the metabolites of florantyrone.","finding":"","journal":"Gastroenterology","studyType":"Clinical Study"},{"pmid":"13791630","year":"1959","title":"Effect of florantyrone on rate of secretion of hepatic bile and on its chemical and physical properties.","finding":"","journal":"Gastroenterology","studyType":"Clinical Study"}],"tags":[{"label":"florantyrone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"zanchol","offLabel":[],"synonyms":["florantyrone","florantyron","fluochol","fluorantyrone","zanchol"],"timeline":[],"approvals":[],"brandName":"Zanchol","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"florantyrone","explanation":"Imagine your body's cells have locks on them, and the key to unlocking the right response is a specific molecule. Florantyrone is like a key that fits into one of these locks, allowing the cell to respond in a way that helps treat a particular condition. However, the exact lock and key mechanism of florantyrone is not yet fully understood.","oneSentence":"Florantyrone works by interacting with a specific cellular target to produce a therapeutic effect.","technicalDetail":"Florantyrone is a small molecule that binds to a specific protein or receptor, triggering a downstream signaling cascade that ultimately leads to a therapeutic effect."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1181","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=FLORANTYRONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T11:29:05.380381","biosimilars":[],"competitors":[],"genericName":"florantyrone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"001206","UNII":"UZ5LMI200P","CHEBI":"CHEBI:135279","INN_ID":"657","UMLSCUI":"C0060463","ChEMBL_ID":"CHEMBL2106357","DRUGBANK_ID":"DB08975","PUBCHEM_CID":"10617","SNOMEDCT_US":"59526004","MESH_SUPPLEMENTAL_RECORD_UI":"C011826"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":6,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1985","pmid":"2932325","title":"Action of drugs and chemical agents on rat liver regeneration.","journal":"Drug and chemical toxicology"},{"date":"1974 Oct","pmid":"4434947","title":"Proceedings: The effect of florantyrone (Zanchol) on the composition of T-tube bile.","journal":"Gut"},{"date":"1965 May-Jun","pmid":"5846616","title":"[Formation of biliverdin by the action of florantyrone].","journal":"Medicina"},{"date":"1961 Dec","pmid":"14483923","title":"A study of the metabolites of florantyrone.","journal":"Gastroenterology"},{"date":"1959 Dec","pmid":"13791630","title":"Effect of florantyrone on rate of secretion of hepatic bile and on its chemical and physical properties.","journal":"Gastroenterology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Zanchol is a small molecule modality with synonyms FLORANTIRONA and FLORANTYRONE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}