{"id":"fipv-0-2ml-im","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Injection site soreness, redness, or swelling"},{"rate":"1-5","effect":"Fever"},{"rate":"5-15","effect":"Irritability or fussiness"},{"rate":"5-10","effect":"Drowsiness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"fIPV contains chemically inactivated (killed) poliovirus particles of serotypes 1, 2, and 3. When administered intramuscularly, it triggers both humoral (antibody) and cellular immune responses without causing disease. The vaccine induces production of neutralizing antibodies that protect against infection if the vaccinated individual is exposed to wild-type or vaccine-derived poliovirus.","oneSentence":"fIPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes, preventing polio infection.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:46:30.727Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of poliomyelitis caused by poliovirus serotypes 1, 2, and 3"}]},"trialDetails":[{"nctId":"NCT04063150","phase":"PHASE4","title":"Immunogenicity of Intramuscular and Intradermal IPV","status":"TERMINATED","sponsor":"Centers for Disease Control and Prevention","startDate":"2019-10-06","conditions":"Poliomyelitis","enrollment":958}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"fIPV (0.2mL) IM","genericName":"fIPV (0.2mL) IM","companyName":"Centers for Disease Control and Prevention","companyId":"centers-for-disease-control-and-prevention","modality":"Biologic","firstApprovalDate":"","aiSummary":"fIPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes, preventing polio infection. Used for Prevention of poliomyelitis caused by poliovirus serotypes 1, 2, and 3.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}