{"id":"finacea-azelaic-acid-foam","safety":{"commonSideEffects":[{"rate":null,"effect":"Pruritus"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Burning sensation"},{"rate":null,"effect":"Scaling"},{"rate":null,"effect":"Dryness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Azelaic acid exerts antimicrobial effects against Cutibacterium acnes and has anti-inflammatory properties that help normalize keratinization and reduce hyperpigmentation. It works through multiple pathways including inhibition of 5-alpha reductase and reduction of free fatty acids on the skin surface, making it effective for acne and rosacea.","oneSentence":"Azelaic acid reduces inflammation and bacterial growth in the skin by inhibiting mitochondrial enzymes and reducing reactive oxygen species production.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:46:42.090Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Rosacea"},{"name":"Acne vulgaris"},{"name":"Post-inflammatory hyperpigmentation"}]},"trialDetails":[{"nctId":"NCT03287791","phase":"PHASE3","title":"A Study to Evaluate Safety and Equivalence of Generic Azelaic Acid Foam and Finacea® Foam in Participants With Rosacea","status":"COMPLETED","sponsor":"Actavis Inc.","startDate":"2016-07-19","conditions":"Rosacea","enrollment":924},{"nctId":"NCT03689010","phase":"PHASE1","title":"To Evaluate the Therapeutic Equivalence and Safety in Treatment of Moderate Facial Rosacea","status":"COMPLETED","sponsor":"Sun Pharmaceutical Industries, Inc.","startDate":"2017-12-12","conditions":"Rosacea","enrollment":1116}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":12,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Finacea® (Azelaic Acid) Foam","genericName":"Finacea® (Azelaic Acid) Foam","companyName":"Actavis Inc.","companyId":"actavis-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Azelaic acid reduces inflammation and bacterial growth in the skin by inhibiting mitochondrial enzymes and reducing reactive oxygen species production. Used for Rosacea, Acne vulgaris, Post-inflammatory hyperpigmentation.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}