{"id":"ferrous-sulfate-higher-concentration","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Gastrointestinal upset (nausea, constipation, abdominal discomfort)"},{"rate":null,"effect":"Dark stools"},{"rate":"5-15","effect":"Epigastric pain"},{"rate":"5-10","effect":"Diarrhea"}]},"_chembl":{"chemblId":"CHEMBL1200830","moleculeType":"Small molecule","molecularWeight":"151.91"},"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"Ferrous sulfate is an iron salt that delivers bioavailable ferrous (Fe2+) iron for absorption in the gastrointestinal tract. At higher concentrations, it increases the amount of iron available for incorporation into hemoglobin and other iron-dependent proteins, correcting iron deficiency anemia. The higher concentration formulation may improve efficacy or reduce dosing frequency compared to standard formulations.","oneSentence":"Ferrous sulfate at higher concentration provides supplemental iron to treat or prevent iron deficiency by increasing circulating iron available for hemoglobin synthesis.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:53:52.822Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia"},{"name":"Iron supplementation in pregnancy or chronic disease"}]},"trialDetails":[{"nctId":"NCT04250298","phase":"NA","title":"Sucrosom5al Iron Supplementation in Blood Donors","status":"COMPLETED","sponsor":"Medical University of Graz","startDate":"2019-11-13","conditions":"Iron-deficiency","enrollment":50},{"nctId":"NCT05544513","phase":"PHASE2","title":"Oral Iron Supplementation for Patients With Chronic Kidney Disease","status":"ACTIVE_NOT_RECRUITING","sponsor":"Universidade Federal Fluminense","startDate":"2022-08-01","conditions":"Chronic Renal Disease, Iron-Deficiency Anemia, Anemia of Chronic Kidney Disease","enrollment":6}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":8,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Ferrous sulfate higher concentration","genericName":"Ferrous sulfate higher concentration","companyName":"Universidade Federal Fluminense","companyId":"universidade-federal-fluminense","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ferrous sulfate at higher concentration provides supplemental iron to treat or prevent iron deficiency by increasing circulating iron available for hemoglobin synthesis. Used for Iron deficiency anemia, Iron supplementation in pregnancy or chronic disease.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}