{"id":"ferrous-gluconate-with-lactoferrin","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Gastrointestinal upset (nausea, constipation, abdominal discomfort)"},{"rate":"common","effect":"Dark stools"},{"rate":"5-15","effect":"Abdominal pain"},{"rate":"5-10","effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Ferrous gluconate is a well-absorbed form of ferrous iron that serves as a substrate for hemoglobin and myoglobin synthesis, addressing iron deficiency. Lactoferrin, an iron-binding protein, facilitates iron absorption in the gastrointestinal tract, reduces pathogenic bacterial colonization, and modulates immune responses through interaction with lactoferrin receptors on immune cells.","oneSentence":"Ferrous gluconate provides bioavailable iron for hemoglobin synthesis, while lactoferrin enhances iron absorption and provides antimicrobial and immunomodulatory effects.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:46:26.729Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia"}]},"trialDetails":[{"nctId":"NCT06252103","phase":"PHASE4","title":"Lactoferrin With Ferrous Gluconate Versus Ferrous Gluconate in Treatment of Iron Deficiency Anemia During Pregnancy","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2023-05-30","conditions":"Lactoferrin With Ferrous Gluconate More Superior Than Ferrous Gluconate Alone in Treatment of Iron Deficiency Anemia","enrollment":40}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Pravotin-sachets®,100mg, Hygint, Egypt) with ferrous gluconate twice daily."],"phase":"marketed","status":"active","brandName":"ferrous gluconate with lactoferrin","genericName":"ferrous gluconate with lactoferrin","companyName":"Ain Shams University","companyId":"ain-shams-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ferrous gluconate provides bioavailable iron for hemoglobin synthesis, while lactoferrin enhances iron absorption and provides antimicrobial and immunomodulatory effects. Used for Iron deficiency anemia.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}