{"id":"ferric-pyrophosphate-liposomal","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Constipation"},{"rate":null,"effect":"Nausea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The liposomal formulation protects ferric pyrophosphate from degradation in the gastrointestinal tract and enhances absorption through the intestinal epithelium. This allows for improved bioavailability and reduced gastrointestinal side effects compared to conventional iron supplements. The iron is then incorporated into hemoglobin and other iron-dependent proteins to restore normal oxygen-carrying capacity and metabolic function.","oneSentence":"Ferric pyrophosphate encapsulated in liposomes delivers iron in a bioavailable form to treat iron deficiency by replenishing systemic iron stores.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:39:40.973Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia"}]},"trialDetails":[{"nctId":"NCT05957328","phase":"PHASE3","title":"A Study to Compare Liposomal Iron With Ferrous Ascorbate in the Treatment of Iron Deficiency Anemia in Children","status":"UNKNOWN","sponsor":"All India Institute of Medical Sciences","startDate":"2023-08","conditions":"Nutritional Anemia","enrollment":96},{"nctId":"NCT05714176","phase":"PHASE4","title":"Comparative Study Between Oral Liposomal Iron,Iron Supported Lactoferrin and IV Iron Dextran in CKD Children","status":"UNKNOWN","sponsor":"Menoufia University","startDate":"2023-02-01","conditions":"CKD - Chronic Kidney Disease","enrollment":90},{"nctId":"NCT04915196","phase":"","title":"Tolerability of Iron Therapy in Women With AUB","status":"UNKNOWN","sponsor":"University of Calgary","startDate":"2021-07-01","conditions":"Iron Deficiency Anemia, Abnormal Uterine Bleeding","enrollment":20},{"nctId":"NCT02760940","phase":"PHASE4","title":"Anemia in Inflammatory Bowel Disease","status":"UNKNOWN","sponsor":"Federal University of Juiz de Fora","startDate":"2016-08","conditions":"Anemia, Bowel Diseases, Inflammatory","enrollment":200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":7,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["liposomal iron","Novoferr"],"phase":"marketed","status":"active","brandName":"Ferric Pyrophosphate Liposomal","genericName":"Ferric Pyrophosphate Liposomal","companyName":"All India Institute of Medical Sciences","companyId":"all-india-institute-of-medical-sciences","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ferric pyrophosphate encapsulated in liposomes delivers iron in a bioavailable form to treat iron deficiency by replenishing systemic iron stores. Used for Iron deficiency anemia.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}